نتایج جستجو برای: giant phyllodes tumors
تعداد نتایج: 232953 فیلتر نتایج به سال:
BACKGROUND Phyllodes tumors are group of biphasic fibroepithelial tumors of the breast of varying malignant potential, ranging from benign tumors to fully malignant sarcomas. According to the Egyptian National Cancer Institute, female malignant cases showed appreciable increase in the recent time period for breast cancer with the malignant phyllodes tumors representing 0.41% of cases in the yea...
We evaluated ultrasonography (US) findings between benign and malignant phyllodes tumors and analyzed diagnostic performance of US-guided core needle biopsy (CNB) for phyllodes tumors. Surgically removed phyllodes tumors of 168 women were divided into two groups according to the benign and malignant (including borderline tumor) groups and 116 were benign and 52 were malignant. On US, the comple...
Phyllodes tumours are rare and account for 0.4% of all breast tumours. The majority of them tend to be less than 5 cms in size with giant tumours larger than 10 cms being about 20% of these cases. They display a broad range of clinical and pathological behavior and are regarded as falling within the spectrum of fibroepithelial neoplasms. Surgery has been the primary modality of treatment. Howev...
Abstract Malignant phyllodes tumors of the breast are fairly rare and fast-growing tumors. They not sensitive to chemotherapy or hormonal therapy. Therefore, primary treatment for malignant is wide surgical excision. Herein, we report a case study which featured 26-year-old woman presented with giant tumor measuring 20 × 17 13 cm. In order reduce chance local recurrence, these types usually inv...
Aims: Strong expression of CD 34 has been described in many tumors. It has been proposed that these lesions arise from long-lived mesenchymal cells. We tested the hypothesis that spindle cell lesions of the breast arise from similar mesenchymal cells in mammary stroma, and to determine the potential diagnostic value of CD 34 immunostaining in these lesions. Methods and results: Sections of fibr...
Exon 2 of MED12, a subunit of the transcriptional mediator complex, has been frequently mutated in uterine leiomyomas and breast fibroadenomas; however, it has been rarely mutated in other tumors. Although the mutations were also found in uterine leiomyosarcomas, the frequency was significantly lower than in uterine leiomyomas. Here, we examined the MED12 mutation in phyllodes tumors, another b...
OBJECTIVE The diagnosis and management of phyllodes tumors is challenging due to its low incidence. The treatment of these tumors is surgery, however the extent of surgery, the application of adjuvant chemotherapy and radiotherapy are still controversial. Therefore, we aimed to evaluate patients who were treated with a diagnosis of phyllodes tumor of the breast in our clinic. MATERIAL AND MET...
Phyllodes tumors of the breast (PTB), also termed phyllodes tumors, are rare tumors (<0.5% of all breast tumors), comprised of both stromal and epithelial elements. They are graded by the use of a set of histologic features into benign, borderline, and malignant subtypes. The mainstay of treatment of non-metastatic phyllodes tumors of the breast is complete surgical resection with wide resectio...
Phyllodes tumors are fibroepithelial lesions and malign forms are rare neoplasms with lower than 1% of all primary breast tumors. Malign forms are usually behaves like sarcomas because they occur in the stroma of the breast. Also proliferation of epithelium occurs and even it is less often, the epithelial component of phyllodes tumors can transform into malignancy too. This epithelial malignanc...
PURPOSE Complete surgical resection is the standard treatment for localized breast phyllodes tumors. Post-surgical treatments are still a matter of debate. We carried out an overview of the literature to investigate the clinical outcome of patients with phyllodes tumor. A retrospective analysis of mono-institutional series has been included as well. METHODS We reviewed all the retrospective s...
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