BACKGROUND AND AIMS Data regarding smoking and alcohol consumption and risk of gastrointestinal bleeding (GIB) are sparse and conflicting. We assessed the risk of major GIB associated with smoking and alcohol consumption in a large, prospective cohort. METHODS We prospectively studied 48,000 men in the Health Professional follow-up Study (HPFS) who were aged 40-75 years at baseline in 1986. W...

Figure 2: Our approximation scheme provides similar results when compared to exact bilateral filtering while being several times faster. From top left to bottom right : a noisy mesh, bilateral filtering, Laplacian filtering, separable bilateral (SBL) filtering decomposed along unsmoothed curvature direction (SBL-u), SBL using random directions (SBL-r) and SBL using smoothed curvature directions...

Sialic acid-binding lectin obtained from bullfrog eggs (SBL) induces cell death in cancer cells but not in normal cells. This antitumor effect is mediated through its ribonuclease (RNase) activity. However, the underlying molecular mechanisms remain unclear. We found that the p38 mitogen-activated protein kinase (MAPK) signaling pathway was activated when SBL induced cell death in three human b...

BACKGROUND The risk factors and clinical sequelae of gastrointestinal bleeding (GIB) in the current era of drug-eluting stents, prolonged dual antiplatelet therapy, and potent P2Y12 inhibitors are not well established. We determined the frequency, predictors, and clinical impact of GIB after percutaneous coronary interventions (PCIs) in a contemporary cohort of consecutive patients treated with...

BACKGROUND Continuous-flow left ventricular assist devices (CF-LVADs) have become the standard of care for patients with end-stage heart failure (HF). While these devices have improved durability compared to earlier generation left ventricular assist devices (LVADs), increased frequency in some complications has been seen, including gastrointestinal bleeding (GIB), pump thrombosis and hemolysis...

This paper concerns message passing based approaches to sparse Bayesian learning (SBL) with a linear model corrupted by additive white Gaussian noise with unknown variance. With the conventional factor graph, mean field (MF) message passing based algorithms have been proposed in the literature. In this work, instead of using the conventional factor graph, we modify the factor graph by adding so...

Electrical load modeling and forecasting are critically important in the electrical network and smart grid. The sparse Bayesian Learning (SBL) algorithm can be utilized to model and forecast the electrical load behavior. The SBL algorithm can solve a sparse weight vector with respect to a kernel matrix for modeling electricity consumption. However, traditional SBL can only handle an electricity...

Particular concerns have been raised regarding the association between non-vitamin K antagonist oral anticoagulants (NOACs) and the risk of gastrointestinal bleeding (GIB); however, current findings are still inconclusive. We conducted a systematic review with a meta-analysis to examine the association between NOACs and GIB in real-life settings. We performed a systematic search of PubMed, EMBA...

INTRODUCTION A myriad of pathologies lead to gastro-intestinal bleeding (GIB). The common clinical presentations are hematemesis, melena, and hematochezia. Endoscopy aids localization and treatment of these lesions. AIMS The aim was to study the differential diagnosis of GIB emphasizing the role of endoscopy in diagnosis and treatment of GIB. PATIENTS AND METHODS A prospective study of pati...

The CommsNet 2013 experiment took place in September 2013 in the La Spezia Gulf, North Tyrrhenian Sea. Organized and scientifically led by the NATO S&T Org. Ctr. for Maritime Research and Experimentation (CMRE, formerly NURC), with the participation of several research institutions, the experiment included among its objectives the evaluation of on-board acoustic Ultra-Short Base Line (USBL) sys...