This study aimed to evaluate changes in glucose metabolism at the early stage and onset of diabetes in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Specifically, after the oral administration of [1, 2, 3-13C]glucose, the levels of exhaled 13CO2, which most likely originated from pyruvate decarboxylation and tricarboxylic acid, were measured. Eight OLETF rats and eight control rats (Long-Evan...

Five patients with sucrase-isomaltase deficiency, and one patient with primary glucose-galactose malabsorption had no increases in breath hydrogen excretion after oral sucrose or glucose. Anaerobic incubation with sugars of stool suspensions from 5 patients with primary sugar malabsorption produced by trace of hydrogen (17 microliter) in only one, while those from 13 or 14 controls produced a m...

UNLABELLED Fructose malabsorption has not been well-defined in Thai populations but there has been increasing consumption of fructose-fortified drinks. OBJECTIVES To assess the incidence of fructose malabsorption and intolerance in Thai normal subjects as well as the facilitating effect of glucose on fructose absorption. METHODS Twenty-five gram of fructose was ingested by 77 subjects (37 m...

objective: helicobacter pylori (h. pylori) is the most common pathogenic bacteria in the stomach. the aim of the current study was to explore the effect of oral garlic administration on bacterial urease activity inside the stomach and its contribution to the treatment of h. pylori infection.   materials and methods: in this clinical trial, 15 patients were studied quantitatively with urease bre...

ba ckground: there have been a number of reports indicating that garlic can inhibit helicobacter pylori ( h. pylori ) in vitro ; however, there is few clinical trials evaluating its effect in human infection. the aim of this study was to assess the effect of garlic consumption on urea breath test (ubt) results in patients with h. pylori infection. m ethods: we performed a randomized case-contro...

BACKGROUND Despite considerable controversy over the inclusion of sucrose in the diets of people with diabetes, the acute metabolism of sucrose is not completely understood. OBJECTIVE Our objective was to investigate the metabolism of the monomeric constituents of sucrose after a high-sucrose meal. DESIGN Three test meals were consumed in a randomized, crossover design by 7 healthy male vol...

BACKGROUND/AIMS Carbohydrate malabsorption is frequent in patients with functional gastrointestinal disorders and in healthy volunteers and can cause gastrointestinal symptoms mimicking irritable bowel syndrome (IBS). The aim of this study was to investigate the prevalence of symptomatic lactose and fructose malabsorption in a large population of patients with IBS-like symptoms based on Rome II...

The diagnosis of small intestinal bacterial overgrowth (SIBO) has increased considerably owing to a growing recognition of its association with common bowel symptoms including chronic diarrhea, bloating, abdominal distention, and the irritable bowel syndrome. Ideally, an accurate and objective diagnosis of SIBO should be established before initiating antibiotic treatment. Unfortunately, no perf...

In paediatric practice proper digestion of carbohydrates is of major importance for adequate growth and development and for prevention of intestinal complaints. Several carbohydrates can be considered in this respect: (a) lactose: the main carbohydrate in the nutrition of early life and also in later life for many white people; (b) starch: the main energy supplier in our food; (c) fructose: a c...