BACKGROUND Gestational diabetes mellitus (GDM) complicates 3-7% of all pregnancies and fetomaternal outcomes are strongly related to early diagnosis of GDM. The aim of this study was to determine the impact of risk factors in the prediction of an abnormal glucose challenge test (GCT). MATERIALS AND METHODS This was a prospective study conducted during 2009-2010 in two prenatal clinics in Rey,...

OBJECTIVE Both gestational diabetes mellitus (GDM) and mild glucose intolerance in pregnancy identify women at increased risk of future type 2 diabetes. In this context, we queried whether metabolic changes that occur in the 1st year postpartum vary in relation to gestational glucose tolerance status. RESEARCH DESIGN AND METHODS Three-hundred-and-ninety-two women underwent glucose challenge t...

OBJECTIVE Gestational impaired glucose tolerance (GIGT), defined by a single abnormal value on antepartum 3-h oral glucose tolerance test (OGTT), is a metabolically heterogeneous disorder. Indeed, the antepartum metabolic phenotype of women with a single abnormal value at 1 h during the OGTT (1-h GIGT) resembles that of women with gestational diabetes mellitus (GDM), whereas GIGT at 2 or 3 h (2...

W e read with great interest the article by Goldberg et al. (1), in which the authors sought to further characterize the metabolic phenotype of the population of pregnant women with the positive glucose challenge test (GCT) test in relation to the time of day when the test was done. They found that women who had GCT done in the afternoon have a better metabolic function and a lower risk of subs...

abstract objective: the aim of this study was evaluating the relationship between maternal serum lipid measured at 13-23 weeks of pregnancy and subsequent glucose intolerance. materials and methods: in a prospective study, 624 pregnant women prior to 23 weeks were eligible for the study. primarily, serum levels of total cholesterol, ldl cholesterol, hdl cholesterol, and triglyceride were measur...

OBJECTIVE A common approach to screening for gestational diabetes mellitus (GDM) is the universal testing of all pregnant women with a 1-h, 50-g glucose challenge test (GCT), followed by a diagnostic oral glucose tolerance test (OGTT) in those in whom the GCT is positive (≥7.8 mmol/L). More important, the GCT is performed at any time of day, but there has been limited study of the effect of tim...

INTRODUCTION Lipid peroxidation (LPO) results from oxidative damage to membrane lipids. Whereas LPO rises in normal pregnancy, the effect of gestational diabetes mellitus (GDM) on this process has not been clearly defined. MATERIALS AND METHOD Fasting blood concentrations of malondialdehyde+4-hydroxyalkenals (MDA+4-HDA), as LPO index, TNFa soluble receptors (sTNF-R1 and sTNF-R2), and soluble ...

Background: The Centers for Disease Control and Prevention estimates that 30 million Americans are living with diabetes and by 2050, 1 out of 3 U.S. adults could develop diabetes. Current screening and diagnostic methods for diabetes mellitus include the oral glucose tolerance test (OGTT), hemoglobin A1c (HbA1c), and fasting plasma glucose (FPG) levels, but each test when used alone will miss a...

Objective: The high prevalence of Gestational Diabetes Mellitus (GDM) in Iran and its maternal and fetal consequences as well as the high risk of its long-term effects including obesity is known. The aim of this study was to evaluate the relationship between body mass index (BMI) in ages of 18 months and 6 years and maternal glucose concentration. Materials and Methods: This is a retrospecti...