نتایج جستجو برای: glutathione s transferase pi

تعداد نتایج: 786180  

2012
Renata Hezova Julie Bienertova-Vasku Milana Sachlova Veronika Brezkova Anna Vasku Marek Svoboda Lenka Radová Igor Kiss Rostislav Vyzula Ondrej Slaby

BACKGROUND Central Europe presents with the highest incidence of sporadic colorectal cancer (CRC) worldwide. As sporadic CRC represents a typical multifactorial disease, it is characterized by intense interaction of the genetic background with the environment. Glutathione S-transferases could act as attractive susceptibility genes for CRC, as they are directly involved in conjugation between gl...

Journal: :Thorax 2010
Matthew S Perzanowski Rachel L Miller Deliang Tang David Ali Robin S Garfinkel Ginger L Chew Inge F Goldstein Frederica P Perera R Graham Barr

BACKGROUND Acetaminophen has been associated with asthma and is in part metabolised via the glutathione pathway. Inner-city minority children have high asthma morbidity and a relatively high frequency of a minor allele variant in the glutathione S transferase Pi gene (GSTP1). We hypothesised that prenatal acetaminophen exposure would predict wheeze at age 5 years in an inner-city minority cohor...

Journal: :Oncology reports 2010
Ivona Hlavata David Vrana Zdenek Smerhovsky Barbara Pardini Alessio Naccarati Pavel Vodicka Jan Novotny Beatrice Mohelnikova-Duchonova Pavel Soucek

Associations of functional single nucleotide polymorphisms in cytochrome P450 1B1, epoxide hydrolase 1, NAD(P)H:quinone oxidoreductase 1, glutathione S-transferase Pi-1 and deletions of glutathione S-transferases Mu-1 and θ-1 with colorectal cancer risk were investigated in a hospital-based case-control study on 495 matched pairs of Czech Caucasians. Polymorphisms were assessed by polymerase ch...

2008
G. Finocchio O. Ozatay L. Torres R. A. Buhrman D. C. Ralph B. Azzerboni

G. Finocchio, O. Ozatay, L. Torres, R. A. Buhrman, D.C. Ralph, B. Azzerboni Dipartimento di Fisica della Materia e Tecnologie Fisiche Avanzate. University of Messina. Salita Sperone 31, 98166, Messina Italy. Hitachi GST, San Jose Res. Ctr., San Jose, CA, 95135 Cornell University, Ithaca, New York 14853-2501, USA. Departamento de Fisica Aplicada. Universidad de Salamanca. Plaza de la Merced s/n ...

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