BACKGROUND Patients with ulcerative colitis (UC) are treated with prednisolone (PSL), which causes adverse side effects. Extracorporeal granulocyte/monocyte adsorption (GMA) with an Adacolumn depletes elevated/activated myeloid lineage leucocytes as sources of inflammatory cytokines. We were interested to evaluate the efficacy, safety and the treatment cost for PSL and GMA. METHODS Forty-one ...

BACKGROUND Granulocyte and monocyte apheresis (GMA) has shown therapeutic efficacy in active ulcerative colitis (UC). We thought that in patients with pouchitis after proctocolectomy for UC, GMA might produce immunological effects in the intestinal mucosa, and improve clinical symptoms. This prospective study was to evaluate the efficacy of GMA for antibiotic-refractory pouchitis after proctoco...

Ein Leitartikel im 4. Heft des Jahres 2005 der GMS ZMed Ausbild [1] stellte mit Genugtuung fest, dass die Gesellschaft für Medizinische Ausbildung (GMA) sich in einer überaus dynamischen Entwicklung befand, sich die Mitgliederzahl in den zwei Jahren zuvor auf 400 verdoppelt hatte und insbesondere jüngereMitglieder die Aktivitäten der GMA belebten, darunter auchmehr als 70 Studierende. Die Wahrn...

We show that a new type of hydrogel can be prepared by covalently inter-linking binary blends of microgel (MG) particles and that the swelling ratio and modulus of the gels can be predicted from their composition. In previous work we established that physical gels of glycidyl methacrylate (GMA) functionalised poly(methyl methacrylate-co-methacrylic acidco-ethyleneglycol dimethacrylate) microgel...

An ANOVA type general multi-allele (GMA) model was proposed in Wang (2014) on analysis of variance components for quantitative trait loci or genetic markers with phased or unphased genotypes. In this study, by applying the GMA model, we further examine estimation of the genetic variance components for genetic markers with unphased genotypes based on a random sample from a study population. In o...

High-grade cellulose (97% α-cellulose content) of 48% crystallinity index was extracted from the renewable marine biomass waste Posidonia oceanica using H₂O₂ and organic peracids following an environmentally friendly and chlorine-free process. This cellulose appeared as a new high-grade cellulose of waste origin quite similar to the high-grade cellulose extracted from more noble starting materi...

Copolymerization of 2-hydroxyethylmethacrylate (HEMA) with glycidylmethacrylate (GMA) in the presence of α-α'-azoisobisbutyronitrile (AIBN) resulted in the formation of hydrogel films carrying reactive epoxy groups. Thirteen kinds of different molecules with pendant NH2 group were used for modifications of the p(HEMA-GMA) films. The NH2 group served as anchor binding site for immobilization of ...

Granulocyte and monocyte adsorptive apheresis (GMA) is reportedly useful as induction therapy for Crohn's disease (CD). However, the effects of GMA on CD64 have not been well characterized. We report here our assessment of CD64 expression on neutrophils before and after treatment with GMA in two patients with CD. The severity of CD was assessed with the CD activity index (CDAI). The duration of...

We propose a compensatory interactive influence of conscientiousness and GMA in task performance such that is most beneficial to for low-GMA individuals. Drawing on trait by interaction theory empirical evidence mechanism low GMA, we contrast our hypothesis with prior research conscientiousness-GMA argue considered different type. observing likely requires (a) considering the appropriate form, ...

Complex economic models often lack the structure for the application of standard techniques in monotone comparative statics. Generalized monotonicity analysis (GMA) extends the available methods in several directions. First, it provides a way of finding parameter moves that yield monotonicity of model solutions. Second, it allows studying the monotonicity of functions or subsets of variables. T...