James J.P. Alix *, Athi Ponnusamy , Debapriya Bhattacharyya , Nigel Hoggard , Richard A. Grünewald e a Sheffield Institute for Translational Neuroscience, University of Sheffield, 385A Glossop Road, Sheffield S10 2HQ, UK Department of Clinical Neurophysiology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, UK Department of Neurosurgery, Royal Hallamshire Hospital...

This article examines encounters with darkness through compositions of houselights and their elimination, arguing that not all brushes are alike. While eradicating directs seeing focuses attention, which already implies a dramaturgical-compositional significance, the design light in auditorium is predominantly relegated to preshow preamble will quickly be switched off. In response, I propose pl...

SNAP-25B is a neuronal protein required for neurotransmitter (NT) release and is the target of Botulinum Toxins A and E. It has two SNARE domains that form a four-helix bundle when combined with syntaxin 1A and synaptobrevin. Formation of the three-protein complex requires both SNARE domains of SNAP-25B to align parallel, stretching out a central linker. The N-terminal of the linker has four cy...