objective(s): granulocyte-colony stimulating factor (g-csf) is used in clinical practice for the treatment of neutropenia and to stimulate generation of hematopoietic stem cells in bone marrow donors. in the present study, the ability of g-csf in mobilizing exogenous bone marrow stem cells (bmscs) from peripheral blood into the brain was tested. we for the first time injected a small amount of ...

two dogs with generalized seizures were evaluated. the dogs were diagnosed with traumatic intracranial hemorrhages based on the history, neurological examinations, and magnetic resonance imaging (mri) of the brain. treatment was started with oxygen, prednisolone and anticonvulsant agents. no further seizure activity was observed after treatment in both dogs, however cushing reflex was detected ...

OBJECTIVES/HYPOTHESIS Granulocyte/macrophage colony-stimulating factor is important in the pathogenesis of acute and chronic inflammatory disease. We hypothesized that granulocyte/macrophage colony-stimulating factor plays a pivotal role in middle ear inflammation and that neutralization of granulocyte/macrophage colony-stimulating factor would inhibit neutrophil migration into the middle ear a...

PURPOSE Granulocyte-colony stimulating factor stimulates proliferation and maturation of granulocyte precursor cells. The influence of this hematopoietic factor on phagocytic function of granulocytes was performed in in vitro experiments. The aim was to find, whether G-CSF applicated to children with neutropenia after chemotherapy influences phagocytic functions of neutrophils and whether evalu...

Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...

The granulocyte-colony-stimulating factor (G-CSF)-producing esophageal carcinosarcoma is extremely rare in esophageal cancer. In the present case, multidisciplinary therapy, which is surgical resection with preoperative chemotherapy, has been effectively treatment to granulocyte-colony-stimulating factor producing esophageal carcinosarcoma of the esophagus.

17. Morstyn G, Campbell L, Lieschke G, et al. Treatment of chemotherapy induced neutropenia by subcutaneously administered granulocyte colony-stimulating factor with optimization of dose and durationof therapy.3 Clin Oncoll989,7,1554-1562. Brugger W, Bross KJ, Lindemann A, Kanz L, Mertelsmann M. Role of hematopoietic growth factor combinations in experimental and clinical oncology. Semin Oncoll...

we present a 24-year-old female referred with non-healing wound of a few days duration on anterior aspect of her right foreleg. biopsy of the wound was reported to be pyoderma gangrenosum on pathologic report. further work up of the patient for high grade fever and occasional leukopenias revealed the diagnosis of cyclic neutropenia. treatment with granulocyte colony-stimulating factor (g-csf) r...