Background: Proanthocyanidin is a potent bioactive antioxidant naturally occurring in grape seed and acts as reactive oxygen species (ROS) scavenger. The aim of this study was to investigate the effects of proanthocyanidinin in experimental ovarian torsion injury.   Methods : Twenty four rats were randomly divided into three groups (n=8). Group 1: the laparotomy group, group 2: ovarian torsio...

Objective(s):Diabetes plays an important role in the induction of the liver injury. Grape seed proanthocyanidin (GSP) have a wide range of medicinal properties against oxidative stress. In this study we evaluated antioxidant effects of GSP on liver in streptozotocin-induced diabetic rats. Materials and Methods: Thirty male Sprague–Dawley rats were divided into three groups: control, untreated d...

As we reported earlier, Muscat Bailey A (MBA) wine has very low proanthocyanidin (PA) content compared with Cabernet Sauvignon (CS) and Merlot wines. Whereas PA concentration in CS was maintained at the maximum level during maceration, that in MBA reached a maximum approximately four days after maceration and drastically decreased thereafter. In this study, the model wine extraction profiles of...

The grape (Vitis vinifera L.) posses several remedy effects. In this study, the anti limnatis nilotica effect of methanolic extract of Vitis vinifera L. plant as well as niclosamide were investigated by anti-leech assay. Distilled water selected as placebo. The mean death time of leeches in groups treated with niclozomide for mature and immature form were 15.4 and 10.1 minutes, respectively. Th...

BACKGROUND Many of flavonoid rich natural products found to have a significant influence on postprandial hyperglycemia, a major risk factor for diabetic complications. Enhancement of insulinotropic gut hormones by inhibition of dipeptidyl peptidase-IV (DPP-IV) are among the newest strategies for treatments of Type 2 diabetes which thought to be the underlying action through which flavonoid can ...

background: proanthocyanidin is a potent bioactive antioxidant naturally occurring in grape seed and acts as reactive oxygen species (ros) scavenger. the aim of this study was to investigate the effects of proanthocyanidinin in experimental ovarian torsion injury.   methods : twenty four rats were randomly divided into three groups (n=8). group 1: the laparotomy group, group 2: ovarian torsion ...

In this study, microscale fermentations were conducted on Vitis vinifera L. cv. Merlot. Five treatments were established varying from 0-100% crushed fruit (25% increments x 5 replicates). Caps were kept submerged throughout the experiment, and fermentation temperatures were maintained at 25 degrees C. Samples were collected throughout fermentation and from the free run and press wine at the tim...