German cockroach extract synergistically regulates tumor necrosis factor-alpha (TNF-alpha)-induced interleukin (IL)-8 expression in human airway epithelial cells. The IL-8 promoter contains nuclear factor (NF)-kappaB, activating protein (AP)-1, and NF for IL-6 (NF-IL6) transcription factor binding regions. Because cockroach extract activates extracellular regulated kinase (ERK), a known activat...

asthma is the most common chronic disease of childhood. exposure to allergens plays an important role in asthma. recently, cockroach has attracted attentions as an important allergen. this study was performed to evaluate cockroach allergy in iranian children with asthma. one hundred children with definite diagnosis of asthma were selected. after obtaining primary information, the severity of th...

Many low-income housing units in the United States continue to have chronic German cockroach, Blattella germanica (L.), infestations and high prevalence of cockroach allergens despite the availability of highly effective cockroach control products. Several studies have demonstrated the greater effectiveness of integrated pest management (IPM) compared with routine chemical interventions in apar...

A growing body of evidence has implicated allergens derived from cockroaches as an important environmental factor that may aggravate asthma in sensitized persons. We present the case of a 30-year-old man with asthma and a cockroach allergy. Allergy skin testing confirmed hypersensitivity to cockroach extract, and a home visit revealed visual evidence of infestation and the presence of Bla g 1 G...

PURPOSE CpG oligodeoxynucleotide (CpG-ODN), a TLR9 agonist, activates innate immunity and induces Th1 response. Although the immune modulatory effect of CpG-ODN has been extensively studied, its function in cockroach extract-induced allergic asthma has not been studied. Here, we investigated the inhibitory function of CpG-ODN in cockroach extract-induced asthma in mice with different treatment ...

Cockroach allergens can lead to serious allergy and asthma symptoms. Termites are evolutionarily related to cockroaches, cohabitate in human dwellings, and represent an increasing pest problem in the United States. The Formosan subterranean termite (Coptotermes formosanus) is one of the most common species in the southern United States. Several assays were used to determine if C. formosanus ter...

The Internet has brought great convenience to society, but copyright disputes have become more complex in the era, and new features about by led changes litigation. Taking photographic works as an example, article briefly analyses characteristics of era introduces “copyright cockroaches” (plaintiffs who seek gain benefits filing numerous lawsuits). Through analysis overseas current situation li...

Airway eosinophilic inflammation is a characteristic feature of allergic asthma. Exposure to allergens produced by the German cockroach (Blattella germanica) is a risk factor for allergic disease in genetically predisposed individuals, and has been linked to an increase in asthma morbidity among cockroach-sensitive inner city children. To determine the role and contribution of specific HLA clas...

BACKGROUND We previously reported significant reductions in cockroach allergen concentrations in urban homes by reducing cockroach infestations. OBJECTIVE To determine the effectiveness of pest control performed by professional entomologists, compared with commercial companies, in reducing cockroach allergen. METHODS This 3-arm randomized controlled trial enrolled 60 cockroach-infested home...