Endometrial and cervical cancers are the most prevalent gynecologic neoplasms. While endometrial cancer occurs in older women, cervical cancer is more prevalente in young subjects. The most common clinical manifestation in these two gynecological cancers is vaginal bleeding. In the first case, diagnosis is made based on histological and imaging evaluation of the endometrium, while cervical canc...

Gynecological medicine is a crucial field that limited by standard methods of screening and detection. Identification biomarkers sensor development for women's cancers illnesses vast aims to improve the health women.

background : ovarian cancer is the leading cause of death among gynecological cancers. changes in the methylation of brca1 and brca2 may be an effective mechanism for breast and ovarian cancer. this study evaluates the protein expression and methylation status of brca2 in iranian patients. methods : we assessed 60 mullerian-type ovarian cancers by methylation-specific pcr assays and immunohisto...

Studies on individual types of gynecological cancers (GCs), utilizing novel expression technologies, have revealed specific pathogenetic patterns and gene markers for cervical (CC), endometrial (EC) and vulvar cancer (VC). Although the clinical phenotypes of the three types of gynecological cancers are discrete, the fact they originate from a common embryological origin, has led to the hypothes...

Krukenbergtumors are ovarian metastases from non-gynecological, mainly gastrointestinal cancers, such as gastric and colorectal cancers. They very rare with a stillpoorlyelucidatedetio-pathogenesis(1). Previousretrospectivestudies have suggestedthatKrukenbergtumors associatedwithapoor prognosis compared to metastaticdiseaseatother sites resultingfrom the sameprimarydisease(2).We report here obs...