Arteriovenous fistula (AVF), is the gold standard access for haemodialysis (HD) patients, as it associated with improved quality of HD and lower infection rates, compared to tunneled dialysis catheters. Complications AV fistulae or grafts include stenosis, thrombosis infection. With regards thrombosis, options rescue thrombolysis thrombectomy both which can now be performed in interventional ra...

BACKGROUND Platelet dysfunction is a well-established disturbance in haemodialysis (HD) patients. Propyl gallate is a synthetic platelet activator with the property to stimulate platelet aggregation. The aim of the present study was to evaluate the influence of a single haemodialysis session on propyl gallate-induced platelet aggregation. METHODS Thirty-nine HD patients were enrolled in the s...

Haemodialysis (HD) patients are at increased risk of vascular access complications with device therapy. We report a case of transvenous defibrillator lead extraction from the ipsilateral side as an HD fistula. The procedure was successfully performed using a hybrid approach, with extraction of the lead with a powered sheath, and surgical cut-down and closure of the subclavian vein defect.

Pregnancy in patients on haemodialysis (HD) is uncommon and carries a high risk of fetal and maternal complications. Multiple pregnancies carry a high risk even in normal individuals; the risk is higher in dialysis patients. We report a patient with end-stage renal disease (ESRD), who conceived while on HD, and had a successful triplet pregnancy. To our knowledge, successful triplet pregnancy i...

BACKGROUND In-centre haemodialysis (ICHD) is the most common dialysis method used by patients worldwide. However, quality of life and clinical outcomes in patients treated via ICHD have not improved for some time. 'High-dose' haemodialysis (HD) regimens--which are longer and/or more frequent than conventional regimens and are particularly suitable to delivery in the home--may offer a route to i...

BACKGROUND Hepatitis C may cause increased levels of oxidative stress that contribute to accumulation of advanced glycation end products (AGEs), which increase the risk of cardiovascular disease (CVD). The aim of this study was to determine the influence of hepatitis C on AGE accumulation in haemodialysis patients. METHODS AGE accumulation was measured by means of skin autofluorescence (AF) i...

BACKGROUND An increase in C-reactive protein (CRP) levels during a single haemodialysis (HD) session has been associated with mortality. These associations, however, are difficult to understand from the current understanding of CRP metabolism. METHODS In 190 Swedish haemodialysis (HD) patients from the Mapping of Inflammatory Markers in Chronic Kidney Disease (MIMICK) cohort, CRP was measured...

Background: More than a decade after the National Institute for Health and Clinical Excellence recommendation of home haemodialysis (home HD) for 10-15% of those needing renal replacement therapy, the uptake across different regions in the UK remains uneven. Methods: This survey is part of the Barriers to Successful Implementation of Care in Home Haemodialysis (BASIC-HHD) study, an observationa...

BACKGROUND Chronic kidney disease (CKD) patients show evidence of chronic inflammation with mononuclear cell activation which is mainly caused by uraemia itself and is exacerbated by haemodialysis. Small fragments of bacterial DNA (DNAb) are ubiquitous contaminants, which are capable of passing through dialyser membranes causing the stimulation of cells of the immune system. The aim of this stu...

We studied dialysis-associated arrhythmia in 48 uraemic patients < 35 years on chronic haemodialysis (HD) (> 3 months). Holter findings showed only minor arrhythmia; atrial in 42% of patients and ventricular in 38%. ST-segment depression > 1 mm was observed in 58% of patients; 80% had arrhythmia, and 36% experienced anginal pain. HD caused a significant increase in QTc, QTdc and Ca2+ level, whi...