One of the relevant phenomenon associated with in-stent restenosis in coronary arteries is an altered haemodynamics in the stented region. Computational fluid dynamics (CFD) offers the possibility to investigate the haemodynamics at a level of detail not always accessible within experimental techniques. CFD can quantify and correlate the local haemodynamics structures which might lead to in-ste...

AIMS Cardiac β-adrenergic receptors (β-AR) are key regulators of cardiac haemodynamics and size. The scaffolding protein A-kinase anchoring protein 79/150 (AKAP5) is a key regulator of myocardial signalling by β-ARs. We examined the function of AKAP5 in regulating cardiac haemodynamics and size, and the role of β-ARs and Ca(2+)-regulated intracellular signalling pathways in this phenomenon. M...

Stress haemodynamics for asymptomatic mitral valve regurgitation may prove helpful in determining the optimal timing for surgery.

Propofol is rapidly acting intravenous agent used for induction in general anaesthesia.It causes pain while administering,being uncomfortable to patients .So an observational study was done compare the effects of different time duration venous occlusion on pretreatment with injection Ketamine prevention at site. After approval ethical committee and written informed consent,ASA grade I II,60 eit...

Spontaneous twin pregnancy is rare in renal transplant recipients, and confers a significant risk, in terms of both transplant dysfunction and fetal complications. Physiological changes in renal haemodynamics may assist in predicting a favourable outcome, but have not been previously reported in these circumstances. We present a case of a successful outcome for both mother and babies, and detai...