نتایج جستجو برای: hair cells
تعداد نتایج: 1409047 فیلتر نتایج به سال:
background: the seladin-1 (selective alzheimer disease indicator-1), also known as dhcr24, is a gene found to be down-regulated in brain region affected by alzheimer disease (ad). whereas, hair follicle stem cells (hfsc), which are affected in with neurogenic potential, it might to hypothesize that this multipotent cell compartment is the predominant source of seladin-1. our aim was to evaluate...
Syntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations
Syntaxin is one of several proteins that may be involved in the docking of synaptic vesicles, synaptic vesicle recycling, and non-synaptic membrane trafficking. Presence of syntaxin has been reported in rat auditory and vestibular end organs. In the current study, we have examined the expression of message for syntaxin 1 in hair cells of the sacculus of the rainbow trout, Oncorhynchus mykiss, w...
Background and Objective: Hair follicle stem cells are multipotent, located in the bulge area, and are highly proliferating. Retinoids have an effect on epidermal differentiation and keratinization. Retinoic acid is used to treat some skin diseases such as Melasma, Acne and Ichthyosis. So, the study of all-trans retinoic acid effect on hair follicle stem cells and determination of the effective...
Background: Alopecia areata is a common, inflamatory and chronic disease of hair and nails, which in some cases result in growth inhibition and lose of hairs. Several factors such as genetic factors, autoimmunity, atopy, stress, fear etc, are known as effective factors in induction and severity of the disease, but the ethiology of this disease is not known exactly so far. Some evidences such as...
Background: Root hair culture is a valuable system to produce recombinant proteins in planta. Antimicrobial peptides (AMPs) are vital parts of the innate immune response found in almost all forms of life. Precise target activity and limited toxicity towards mammalian cells make them suitable candidate molecules to combat evolving drug-resistant microorganisms. The aim of the present study...
Hair follicles are surrounded by the dermis, but cells part of epidermis and separated from dermis basal lamina layer. The main aim study is to design evaluation versatile Herbal Oil prevent control hair-related problems. objectives Provides hair conditioning, Prevention & fall, Reduce scalp irritation, Prevents premature greying hair, Treats Dandruff, Relieves all types headaches especiall...
background outer hair cells' (ohcs') dysfunctions as the extent of temporary and permanent threshold shifts (tts and pts) and cochlear damage were assessed in rabbits exposed to continuous noise methods twelve new zealand white rabbits were studied in noise (n) (n=6; exposed to continuous noise; 95 db spl, 500-8000 hz for 8 h per day during 5 consecutive days) and control (c) (n=6; no...
Loss of cochlear hair cells in mammals is currently believed to be permanent, resulting in hearing impairment that affects more than 10% of the population. Here, we developed two genetic strategies to ablate neonatal mouse cochlear hair cells in vivo. Both Pou4f3(DTR/+) and Atoh1-CreER™; ROSA26(DTA/+) alleles allowed selective and inducible hair cell ablation. After hair cell loss was induced a...
In mammals, auditory hair cells are generated only during embryonic development and loss or damage to hair cells is permanent. However, in non-mammalian vertebrate species, such as birds, neighboring glia-like supporting cells regenerate auditory hair cells by both mitotic and non-mitotic mechanisms. Based on work in intact cochlear tissue, it is thought that Notch signaling might restrict supp...
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