Abstract: Cortical long-term depression (LTD) and long-term potentiation (LTP) are thought to be important mechanisms for the plasticity of topographic sensory maps, especially in rodent somatosensory (barrel) cortex. At the layer (L) 4 to L2/3 synapse in rat barrel cortex, LTP and LTD can be induced by spike timing-dependent plasticity (STDP) in which the precise, millisecond-scale timing of p...
