Grob fragmentation of suitably designed bicyclic species often generates novel organic skeletons in a facile manner. Herein, we report a comprehensive account of an effective acid-catalyzed Grob fragmentation of trihalonorbornyl ketones to dihalophenol derivatives in good yields. The transformation entails tri-n-butyltin hydride (TBTH) mediated regioselective reduction of one of the two bridgeh...

An enantioselective rhodium(I)-catalyzed Pauson–Khand reaction (PKR) using 1,6-chloroenynes that contain challenging 1,1-disubstituted olefins is described. In contrast to the previous studies with these types of substrates, which are only suitable for a single type tether and alkyne substituent, new approach results in more expansive substrate scope, including carbon heteroatom tethers polar n...

We have studied the direct synthesis of hydrogen peroxide using a catalytic system consisting palladium supported on silica bifunctionalized with sulfonic acid groups and bromide in absence halide promoters solution. Catalysts several substituents were employed catalyst synthesis. The prepared samples characterized by TXRF, XPS, decomposition. characterization indicated presence only (II) speci...

Lead-free halide double perovskites (DPs) are highly tunable materials in terms of chemical composition and optical properties. One the most widely reported DPs is Cs2AgBiBr6, which envisaged as a promising absorber for photovoltaics. Nevertheless, its bandgap (around 1.9–2.3 eV) remains too large common tandem solar cells. In this work, we report mechanochemical synthesis Sn-, Ge-, Zn-substitu...

• Synthesis of new DESs and DES–like systems based on polyols as HBDs halide salts HBAs. Innovative DES design approach inspired by the necessity rigorous classification true DESs. Unveiling reduction process diazonium in a formed glycerol potassium fluoride. Mechanistic study DFT calculations electrochemical measurements. Combined theoretical experimental promotes an unprecedented successful i...

The effect of alkyl substituents on the C-phenyl and/or the N-Phenyl ring of benzophenylhydroxamic acid on their molecular structure and hydrogen bonding has been investigated. The predominant configuration in CHCl3 is determined by steric and electronic effects. Substituents on the C-phenyl ring favor the cis configuration, while substituents in the N-phenyl ring favor a trans c...

Halide ions could be visualized via fluorescence quenching in microcolumn ion chromatography. The fluorescence of quinine sulfate, which was contained in an acidic eluent, was quenched by halide ions. The observed fluorescence quenching values increased in this order: iodide, bromide, and chloride. The present detection system was relatively sensitive to halide ions except for fluoride: other a...

Haloalkane dehalogenase converts haloalkanes to their corresponding alcohols and halides. The reaction mechanism involves the formation of a covalent alkyl-enzyme complex which is hydrolyzed by water. The active site is a hydrophobic cavity buried between the main domain and the cap domain of the enzyme. The enzyme has a broad substrate specificity, but the kcat values of the enzyme for the bes...

the effect of alkyl substituents on the c-phenyl and/or the n-phenyl ring of benzophenylhydroxamic acid on their molecular structure and hydrogen bonding has been investigated. the predominant configuration in chcl3 is determined by steric and electronic effects. substituents on the c-phenyl ring favor the cis configuration, while substituents in the n-phenyl ring favor a trans configuration. t...

Haloalkane dehalogenase (DhlA) hydrolyzes short-chain haloalkanes to produce the corresponding alcohols and halide ions. Release of the halide ion from the active-site cavity can proceed via a two-step and a three-step route, which both contain slow enzyme isomerization steps. Thermodynamic analysis of bromide binding and release showed that the slow unimolecular isomerization steps in the thre...