HREE loci controlling the synthesis of serum proteins in the pig have been Tidentified to date. KRISTJANSSON ( 1960a, b) has identified two alleles controlling the synthesis of transferrins in the pig and has demonstrated (1961) three alleles involved in the synthesis of pig haptoglobins. ASHTON (1960) has described three Yhread protein” phenotypes and on the basis of preliminary mating data ha...

Haptoglobin, the haptoglobin-hemoglobin receptor CD163, and the heme oxygenase-1 are proteins with a well-established function in the clearance and metabolism of "free" hemoglobin released during intravascular hemolysis. This scavenging system counteracts the potentially harmful oxidative and NO-scavenging effects associated with "free" hemoglobin, and, furthermore, elicits an anti-inflammatory...

1. A procedure for the rapid, accurate estimation of haptoglobin in serum and purified preparations is described, based on the peroxidase activity of haemoglobin in its complexes with haptoglobin. 2. Hydrogen peroxide, guaiacol and methaemoglobin reagents are used, under well-defined conditions which reduce the peroxidase activity of free haemoglobin essentially to zero. The reaction is followe...

background: introduction: searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. there are many biomarkers reported for neonatal sepsis. haptoglobin is an acute phase reactants which rise in response to infection and injuries. in this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...

The various antigenic determinants of serum haptoglobins (Hp) may be studied semiquantitatively in a radioimmunoassay system. Using three antisera of overlapping specificities, we constructed an antigenic model of the various Hp phenotypes comprising four distinct determinants. This adds a new determinant, situated near the hemoglobin binding site, to the three determinants reported in the lite...

Changes in the serum haptoglobin level have been reported in certain forms of anaemia (Allison and ap Rees, 1957; Allison, 1958; Nosslin and Nyman, 1958; Nyman, Gydell, and Nosslin, 1959), in hepatobiliary disease (Owen, Mackay, and Got, 1959) and in various inflammatory and chronic diseases (Jayle and Boussier, 1955; Allison and Blumberg, 1958). A simple colorimetric procedure for the determin...