The special formulation MA212 (Rosaxan) is composed of rosehip (Rosa canina L.) puree/juice concentrate, nettle (Urtica dioica L.) leaf extract, and devil's claw (Harpagophytum procumbens DC. ex Meisn. or Harpagophytum zeyheri Decne.) root extract and also supplies vitamin D. It is a food for special medical purposes ([EU] No 609/2013) for the dietary management of pain in patients with gonarth...

In an attempt to scientifically appraise the ‘healing po Harpagophytum procumbens DC [family: Pedaliaceae], efficacy and safety of the medicinal plant product, we hav effects of the plant’s secondary root aqueous extract (HP rabbit isolated gastro-intestinal smooth muscle preparation animal study indicate that relatively low to high doses secondary root aqueous extract (HPE, 10–1000 μg/ml) sign...

Devil's claw (Harpagophytum procumbens): pharmacological and clinical studies SIR, Over the last few years a number of reports have appeared in local newpapers in the North of England and Scotland claiming 'miraculous' results for treatment with devil's claw in patients with both adult and juvenile rheumatoid arthritis.1 2The preparation used was a tablet prepared from an aqueous extract of the...

Phenylethanoids are a group of natural water-soluble compounds with high biological value, which could potentially be commercially produced by hairy root cultures. Thus, we have examined the capacity of transformed root cultures of Devil's claw (Harpagophytum procumbens) to accumulate four phenylethanoid glycosides -beta-OH-verbascoside, verbascoside, leucosceptoside A, and martynoside--in shak...