This course is motivated by tremendous progress in the development and accessibility of high dynamic range technology (HDR) that happened just recently, which creates many interesting opportunities and challenges in graphics. The course presents a complete pipeline for HDR image and video processing from acquisition, through compression and quality evaluation, to display. Also, successful examp...

In the Pseudo-Multiple-Exposure-Based Tone Fusion with Local Region Adjustment [1], it introduces a framework for inverse tone mapping which uses only one Low Dynamic Range (LDR) image to evaluate High Dynamic Range (HDR) image. First, map LDR image to HDR images using S curve. By changing the parameters of S curve, we can get different EV scenes. Then, segment the image into four different lum...

Diet induced obese (DIO) mice can be stratified according to their weight gain in response to high fat diet as low responders (LDR) and high responders (HDR). This allows the study of β-cell failure and the transitions to prediabetes (LDR) and early diabetes (HDR). C57BL/6N mice were fed for 8 weeks with a normal chow diet (ND) or a high fat diet and stratified as LDR and HDR. Freshly isolated ...

We present a novel approach that allows users to intuitively and interactively manipulate High Dynamic Range (HDR) images using commonly available Low Dynamic Range (LDR) displays. This solves the problem of how to draw with contrasts that are much larger than the monitor can display. Whereas commercial HDR-enabled drawing programs manipulate tone mapped representations of HDR images, we provid...

Recent advances in high dynamic range (HDR) capture and display technologies have attracted a lot of interest from scientific, professional, and artistic communities. As in any technology, the evaluation of HDR systems in terms of quality of experience is essential. Subjective evaluations are time consuming and expensive, and thus objective quality assessment tools are needed as well. In this p...

Analyses have been completed to evaluate different operating strategies for the Hijiori Long Term Circulation Test (LTCT). To ensure that the Geocrack2D model used to represent the LTCT was valid, 1991-1996 testing at Hijiori was first simulated. After reasonable matches were obtained with the existing data, the model was used to predict behavior during the two year long LTCT. Five cases were a...

BACKGROUND We have previously used the ATAD5-luciferase high-throughput screening assay to identify genotoxic compounds with potential chemotherapeutic capabilities. The successful identification of known genotoxic agents, including the histone deacetylase inhibitor (HDACi) trichostatin A (TSA), confirmed the specificity of the screen since TSA has been widely studied for its ability to cause a...

BRCA1 is essential for homology-directed repair (HDR) of DNA double-strand breaks in part through antagonism of the nonhomologous end-joining factor 53BP1. The ATM kinase is involved in various aspects of DNA damage signaling and repair, but how ATM participates in HDR and genetically interacts with BRCA1 in this process is unclear. To investigate this question, we used the Brca1S1598F mouse mo...

Trimodality therapy consisting of high dose rate (HDR) brachytherapy combined with external beam radiation therapy (EBRT), neoadjuvant hormonal therapy (NHT) and adjuvant hormonal therapy (AHT) has been used to treat localized high-risk prostate cancer. In this study, an analysis of patients receiving the trimodality therapy was performed to identify prognostic factors of biochemical relapse-fr...

We investigated the spatial summation effect on pedestals with difference luminance. The targets were luminance modulation defined by Gaussian functions. The size of the Gaussian spot was determined by the scale parameter (standard deviation, σ) which ranged from 0.13 to 1.04. The local luminance pedestal (2 radius) had mean luminance ranged from 2.9 to 29cd/m. The no-pedestal condition had a m...