OBJECTIVE The associations between oral diseases and increased risk of pancreatic cancer have been reported in several prospective cohort studies. In this study, we measured variations of salivary microbiota and evaluated their potential associations with pancreatic cancer and chronic pancreatitis. METHODS This study was divided into three phases: (1) microbial profiling using the Human Oral ...

Persons with posttraumatic stress disorder (PTSD) have been shown to display elevated baseline cardiovascular activity and a heightened physiological reactivity to trauma-related stimuli. Study 1 examined differences in baseline heart rate (HR) and HR reactivity in 68 survivors of motor vehicle accidents (MVAs) and healthy controls without MVA. MVA survivors with PTSD (n=26), subsyndromal PTSD ...

Background: HLA-B*27 is strongly associated with ankylosing spondylitis (AS). It represents a family of alleles that differ among ethnic groups. Objective: The aim of this study was to determine the distribution of HLA-B*27 alleles in AS patients and healthy controls in Isfahan (Iran). Methods: Sixty AS patients and 430 healthy blood donors were selected. All subjects were HLA-B*27 positive by ...

background: hla-b*27 is strongly associated with ankylosing spondylitis (as). it represents a family of alleles that differ among ethnic groups. objective: the aim of this study was to determine the distribution of hla-b*27 alleles in as patients and healthy controls in isfahan (iran). methods: sixty as patients and 430 healthy blood donors were selected. all subjects were hla-b*27 positive by ...

Objective: Up to now, no investigation has applied a complementary approach in terms of the emotional and affective temperament to study Panic Disorder (PD), Post-Traumatic Stress Disorder (PTSD), and healthy controls. Hence the current study aimed to investigate the affective and emotional temperaments among individuals with PD, PTSD, and healthy controls using an integrative temperament scale...

The clinical presentation of diabetes sometimes overlaps, contributing to ambiguity in the diagnosis. Thus, circulating pancreatic islet-enriched microRNAs (miRNAs) might be useful biomarkers of β-cell injury/dysfunction that would allow more accurate subtyping of diabetes. We measured plasma levels of selected miRNAs in subjects with prediabetes (n = 12), type 2 diabetes (T2D, n = 31), latent ...

Background: Patients with inflammatory rheumatic diseases such as rheumatoid arthritis (RA), psoriatic (PsA) and ankylosing spondylitis (AS) are at a higher risk for developing cardiovascular (CVD) than the general population. This increased is partly due to incidence of traditional (CV) factors, hypertension dyslipidemia, underlying systemic inflammation. During past two decades, burden inflam...

Fluorescence polarisation of 1,6-diphenyl-1,3,5-hexatriene was used to study the lymphocyte membrane in rheumatoid arthritis. The increase of polarisation value in the patients (n = 27) compared with healthy controls (n = 32) suggests a decrease of membrane fluidity. Moreover, erythrocyte sedimentation rate (ESR) and plasma fibrinogen concentrations were positively correlated with lymphocyte fl...