BACKGROUND The assessment of cardiac iron overload in thalassemia major has been considered as an important predictive factor of heart injury. The magnetic resonance imaging (MRI)-derived relaxation time parameter (T2*) varies inversely with iron level, and elevated myocardial iron levels by T2* are associated with depressed left ventricular (LV) ejection fraction (EF). We compared echocardiogr...

Abdullah H, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-219793 Description Conjoined twins are very rare with incidence of 1 per 250 000 live births. Fetal MRI is an important adjunct to ultrasound particularly in evaluation of complex fetal anomalies and organ positions. 3 This case report illustrates our first experience in MRI fetal of conjoined twins with the current available sequences....

OBJECTIVES This study aimed to determine whether the myocardial T2 relaxation time, determined using a black-blood magnetic resonance imaging (MRI) sequence, could predict acute heart transplant rejection. BACKGROUND The use of black-blood MRI sequences allows suppression of the confusing influence of blood signal when myocardial T2 is calculated to detect myocardial edema. METHODS A total ...

Results Three groups of patients were identified: 27 patients (13 females, mean age 40.12±10.31 years) treated with desferioxamine (DFO mean dosage 37.52±8.69 mg/kg/ die), 23 patients (14 females, mean age 34.73±10.67 years) treated with deferiprone (DFPdosage 71.70 ±14.46mg/kg/die) and 14 patients (9 females, mean age 36.63±10.92 years) treated with deferasirox (DFX mean dosage 27.75±5.04 mg/k...

background: in recent years, the success in management of thalassemic patients, has allowed for some previously unrecognized complications including renal abnormalities to emerge. this prospective study aimed to investigate kidney iron overload by means of mri t2* and also renal function based on laboratory tests for early markers of glomerular and tubular dysfunction among adult iranian transf...

Background: To assess MRI in diagnosing endometriotic lesions, emphasizing T2*weighted imaging efficacy. Materials and Methods: This prospective study of 48 females (22-38 years, average 29.6) clinically suspected of endometriosis from September 2009 to April 2012. MRI was performed with a 1.5 T imager (Siemens) with a body array coil. T1, T2 and T2* weighted (2D-FLASH) sequences were obtained ...

INTRODUCTION Patients with heart transplant are screened for silent graft rejection by recurrent endomyocardial biopsies. MRI can detect the presence of oedema non-invasively by quantitatively measuring changes of the transverse relaxation time T2 in the myocardium. Several monocentric studies have shown that T2 quantification could help detect graft rejection in a less invasive way. DRAGET is ...

PURPOSE To assess the transferability of the magnetic resonance imaging (MRI) multislice multiecho T2(*) technique for global and segmental measurement of iron overload in thalassemia patients. MATERIALS AND METHODS Multiecho T2(*) sequences were installed on six MRI scanners. Five healthy subjects (n = 30) were scanned at each site; five thalassemia major (TM) patients were scanned at the re...

purpose t1wi (t1 weighted image) was acquired in order to grade bone fusion following the studies by fifa (federation internationale de football associations). research using images other than t1wi has not been reported. the aim of this study is to evaluate the grade of epiphyseal fusion by t2* weighted images (t2*wi) and to investigate new findings on t2*wi as compared with t1wi. methods a tot...

Background Iron toxicity is key factor for tissue damage in ironoverloaded patients, with induced heart failure as the main cause of death. T2*-weighted MRI has been established as the method of choice for evaluating iron-content with strong correlation with biopsy, where T2* < 20 ms and T2* < 10 ms at 1.5T indicate iron overload and severe iron overload, respectively. Recently-introduced duale...