Spatial relations within and between objects can be represented either coordinately or categorically. Coordinate representations concern metric and precise relations, and are strongly associated with right parietal cortex activity, while categorical representations relate to more qualitative, abstract relations, and have shown to have a, somewhat weaker, relationship with left parietal cortex a...

In most humans, language is lateralized to the left side of the brain. It has been speculated that this hemispheric specialization is a prerequisite for the full realization of linguistic potential. Using standardized questionnaires and performance measures, we attempted to determine if there are behavioural correlates of atypical, i.e. right-hemispheric and bilateral, language lateralization. ...

Hemispheric lateralization is a frequently encountered phenomenon of cortical function. It describes the functional specialization of a region on one side of the brain for a given task. It is well characterized in motor and sensory, as well as language systems and becomes more and more known for various cognitive domains. While in the adult healthy brain hemispheric lateralization is mostly set...

Hemispheric lateralization for language production and its relationships with manual preference and manual preference strength were studied in a sample of 297 subjects, including 153 left-handers (LH). A hemispheric functional lateralization index (HFLI) for language was derived from fMRI acquired during a covert sentence generation task as compared with a covert word list recitation. The multi...

Speech production is a left-lateralized brain function, which could arise from a left dominance either in speech executive or sensory processes or both. Using functional magnetic resonance imaging in healthy subjects, we show that sensory cortices already lateralize when speaking is intended, while the frontal cortex only lateralizes when speech is acted out. The sequence of lateralization, fir...

Studies show that emerging left hemisphere lateralization for word reading is correlated with emerging left hemisphere lateralization for high spatial frequency (HSF) information. However, it is currently unclear whether left lateralization is partially caused by a pre‐ existing left hemisphere bias for high spatial frequency visual information (such as that found in words), or if the left hemi...

Objectives: The main goal of this study was to investigate and compare the neural substrate of two children's profiles of high intelligence quotient (HIQ). Methods: Two groups of HIQ children were included with either a homogeneous (Hom-HIQ: n = 20) or a heterogeneous IQ profile (Het-HIQ: n = 24) as defined by a significant difference between verbal comprehension index and perceptual reasoning ...

Handedness and language lateralization are partially determined by genetic influences. It has been estimated that at least 40 (and potentially more) possibly interacting genes may influence the ontogenesis of hemispheric asymmetries. Recently, it has been suggested that analyzing the genetics of hemispheric asymmetries on the level of gene ontology sets, rather than at the level of individual g...

Background: Hemispheric asymmetry studies of working memory are mainly carried out in western countries. Data on Chinese is limited in this area of research. On the other hand, working memory assessment can be limited by the temporal resolution of the imaging modality as well as the design of the cognitive paradigm. These methodological limitations infl uence result interpretation hence hinder ...