BACKGROUND AND PURPOSE Whether the excision of hemosiderin surrounding cerebral cavernous malformations (CCMs) is necessary to achieve a seizure-free result has been the subject of debate. Here, we report a systematic review of related literature up to Jan 1, 2015 including 594 patients to assess the effect of hemosiderin excision on seizure outcome in patients with CCMs by meta-analysis. MET...

The pilocytic astrocytoma is only rarely associated with gross intratumoral hemorrhage despite rich vasculature and blood vessel changes, accompanied often by perivascular depots of hemosiderin. We report an unusual case of pigmented cerebellar pilocytic astrocytoma presenting with posttraumatic hemorrhage in a 38-year-old man with no history related to the tumor. CT and MRI examination after h...

The purpose of this study was to examine whether a single episode of traumatic subarachnoid hemorrhage (tSAH) could cause superficial siderosis of the central nervous system (SS-CNS).This study was approved by the local ethics committee. Thirty-two patients with a history of a single episode of tSAH were enrolled in the study. An episode of tSAH was confirmed in patients based on a CT scan or a...

The paper by Thulborn et al. [1] on the distribution of ferritin and hemosiderin in cerebral hemorrhage implies that Perls Prussian blue stains hemosiderin and does not stain ferritin. This was most surprising to us, as we had just obtained excellent Perls stains of ferritincontaining regions of the brain [2] (Fig . 1 ). We think that given the current interest in iron in the brain and its effe...

Although hemosiderosis develops in many circumstances (1) in man and animals, and though hemosiderin has long been recognized as an important product of iron metabolism, the formation and structure of hemosiderin in tissues have not as yet been elucidated at fine structure levels. In recent years numerous studies have indicated a close chemical relationship between the iron storage compound fer...

superficial siderosis (ss) is a rare disease which affects people in all ages and both sexes, but three times more in men. pathological etiology is deposition of hemosiderin (a product of the breakdown of blood) in leptomeninges, subpial layer, ependymal surface and other parts of central nervous system (cns) and typically leads to neurological dysfunction and progressive irreversible signs and...

OBJECTIVE To present a detailed explanation on the processing of magnetic susceptibility weighted imaging (SWI), demonstrating the effects of echo time and sensitive mask on the differentiation between calcification and hemosiderin. MATERIALS AND METHODS Computed tomography and magnetic resonance (magnitude and phase) images of six patients (age range 41- 54 years; four men) were retrospectiv...