OBJECTIVE This study was designed to determine the current age-related hepatitis A virus (HAV) seroprevalance, vaccination status of children and to evaluate the epidemiological shift in HAV serostatus living in Tekirdağ, which is located in Thrace region, the European part of Turkey. METHODS Children 6 months-12 years of age with simple health problems were included. Blood samples were studi...

OBJECTIVE Chronic hepatitis C is a major long-term problem for children who survive cancer. Interferon (IFN)-alpha has been shown to be effective in treating patients with chronic hepatitis C; however, the rate of sustained response is low. Combining IFN-alpha and ribavirin (RBV) has been shown to significantly improve the response in adult patients with chronic hepatitis C. The aim of this pil...

BACKGROUND Adherence to medication is an important aspect of preventing drug resistance and treatment failure in patients receiving nucleos(t)ide analogues for chronic hepatitis B. AIMS To assess adherence to nucleoside/nucleotide analogues in chronic hepatitis B treatment and to determine factors associated with non-adherence. STUDY DESIGN Cross-sectional study. METHODS The study enrolle...

Hepatitis E virus (HEV) is the major cause of epidemic and sporadic hepatitis globally. Outbreaks are associated with fecal contamination of drinking water, yet the environmental reservoir of HEV between epidemics remains unclear. In contrast to neighboring countries, where epidemics and sporadic disease co-occur, HEV-endemic communities in rural Bangladesh seldom report outbreaks; sporadic hep...

aim : the aim of study was to determine the preliminary result of treatment with pegasys in iranian chronic hepatitis b patients (with genotype d) referred to tehran hepatitis center (thc). background : the genotype of hbv and ethnicity of the patients can affect the response rate to pegasys. patients and methods : during 2006-2008, 12 patients with naïve chronic hepatitis b (genotype d) that r...

BACKGROUND Although the epidemiology of hepatitis B (HBV) and C (HCV) now seems well established for Western European countries, in Central and Eastern Europe < 50% of all dialysis centres routinely test for hepatitis C antibodies since testing is not available or is not applied to all patients. This study describes the prevalence, risk factors and clinical significance of HBV and HCV infection...

Treatment for chronic hepatitis B in Brazil are funded by the Ministry of Health and by the state Departments of Health. Clinical protocol and therapeutic guidelines approve the use of adefovir, entecavir, interferon-α, lamivudine, and tenofovir for the treatment of chronic hepatitis B. The aim of this study was to establish the profile of users of these drugs in the state of Paraná. A cross-se...

Pegvisomant (PEGv) is a growth hormone receptor antagonist approved for the treatment of acromegaly; one of its documented adverse effects is reversible elevation of hepatic enzymes. We report a 39-year-old male acromegalic patient with a pituitary macroadenoma who underwent transsphenoidal surgery. The patient's condition improved but GH and IGF-I levels did not normalize; as a consequence, we...

We read with great interest the article, “efficacy of hepatitis B vaccine in those who lost hepatitis B surface antigen during follow-up” by Taheri et al. published in Hepatitis Monthly (1). In this article, the authors assessed the efficacy of HBV vaccine in those who lost their HBsAg without seroconverssion to anti-HBs antibody with no detectable anti-HBs antibody and HBV DNA in their sera. T...