objective(s): in the present study, our aim was to investigate the possible protective effects of epigallocatechin gallate (egcg) on lipopolysaccharide (lps)-induced hepatotoxicity by using hep3b human hepatoma cells. specifically, the study examines the role of some proinflammatory markers and oxidative damage as possible mechanisms of lps-associated cytotoxicity. consequently, the hepatocellu...

Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination early diagnosis of hepatoma, complications their preventions treatments, etc.

Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination early diagnosis of hepatoma, complications their preventions treatments, etc.

Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination early diagnosis of hepatoma, complications their preventions treatments, etc.

Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination early diagnosis of hepatoma, complications their preventions treatments, etc.

Hepatoma Research is an open access journal and focuses on all topics related to hepatoma. The following articles are especially welcome: pathogenesis, clinical examination early diagnosis of hepatoma, complications their preventions treatments, etc.

protein tyrosine phosphatases (ptpases) regulate tyrosine phosphorylation of target proteins involved in several aspects of cellular functions. enzyme activities of the ptpases in cytosolic and particulate fractions of rat ascites hepatoma cell lines were determined and compared with those of normal rat liver. our present data revealed that although there was no neoplatic-specific alteration of...

BACKGROUND Chitosan oligosaccharide, the degradation products of chitin, was reported to have a wide range of physiological functions and biological activities. In this study, we explored the inhibitory effect of Chitosan oligosaccharide on human hepatoma cells. MATERIALS AND METHODS MTT assay was applied to detect cell viability of the human hepatoma cells treated with Chitosan oligosacchari...

OBJECTIVES Hypoxia is a common phenomenon in solid tumors, associated with chemotherapy and radiotherapy resistance, recurrence and metastasis. Hyperbaric oxygen (HBO) therapy can increase tissue oxygen pressure and content to prevent the resistance, recurrence and metastasis of cancer. Presently, Sorafenib is a first-line drug, targeted for hepatocellular carcinoma (HCC) but effective in only ...

To explore the effect of esomeprazole on biological characteristics hepatoma cells by regulating protein kinase B/forkhead box O3 pathway. Hepatoma cell lines were cultured and subcultured divided into model group, low dose group high group. The changes proliferation, colony formation apoptosis in each expression levels related proteins pathway detected. Esomeprazole inhibited tumor a time dose...