Purpose: To determine the true etiology of cases putative recurrent shingles referred to a dermatology clinic. Methods: A prospective cohort study patients aged 15-87 years with reported herpes zoster was conducted. Vesicular fluid and serology for simplex 1, 2, varicella virus immunoglobulins were obtained from presenting vesicles. Biopsies ambiguous presentations. Results: 44 (56%) had eviden...

In this study we aimed to determine the incidence of herpes simplex virus (HSV) in the lungs of burns patients, and its association with the presence of adult respiratory distress syndrome (ARDS) and pneumonia. Haematoxylin and eosin (H&E), and immunohistochemical (IHC) staining for HSV was performed on lung tissue from 54 patients who had died following burn injury and from nine control cases....

Orolabial and genital herpes are common conditions caused by simplex virus (HSV) that affect many individuals. Although skin findings may mimic other conditions, an HSV infection still be diagnosed clinically. We present a case of polymerase chain reaction (PCR) negative orolabial in young male with high-risk social history. testing was negative, oral clinically the patient adequately treated I...

The herpes simplex virus (HSV) frequently establishes a latent state in neurons, which can then be reactivated from the infected neurons. Quantifying the single-cell viral load is essential for understanding latency and reactivation of this virus. In this chapter the methods of laser capture microdissection and quantitative real-time polymerase chain reaction with in situ hybridization have bee...

Background and Aims: Herpes simplex virus type 1 (HSV-1) belonging to herpes viridae family is a normal human pathogen with benign lesions in immunocompromised patients which creates serious problems. Acyclovir is used to treat herpetic infections. Because of developing drug-resistant strains, the use of medicinal plants and their related compounds with fewer side effects is considered for the ...

Nongenital herpes simplex virus type 1 is a common infection usually transmitted during childhood via nonsexual contact. Most of these infections involve the oral mucosa or lips (herpes labialis). The diagnosis of an infection with herpes simplex virus type 1 is usually made by the appearance of the lesions (grouped vesicles or ulcers on an erythematous base) and patient history. However, if un...

BACKGROUND Herpesvirus infections often complicate the clinical course of patients with inflammatory bowel disease; however, invasive disease due to herpes simplex virus is distinctly uncommon. METHODS We present a case of herpes simplex virus colitis and hepatitis, review all the previously published cases of herpes simplex virus colitis, and discuss common clinical features and outcomes. We...

Aim: The aim of this case presentation was to highlight the importance awareness two different coexisting pathologies, as well emphasise that early diagnosis and prompt management are essential manage pemphigus vulgaris. Pemphigus vulgaris is a rare, life-threatening autoimmune disease characterised by presence blisters on surface oral mucosa caused antibodies against adhesion molecules cell ke...

A patient with herpes simplex virus encephalitis is described. The polymerase chain reaction (PCR) was used to confirm the diagnosis in cerebrospinal fluid. PCR allows the rapid diagnosis of many infectious organisms, such as HSV, in which prompt diagnosis is essential.