Abstract Mercury (Hg) concentrations have significantly increased in oceans during the last century. This element accumulates marine fauna and can reach toxic levels. Seafood consumption is main pathway of methylmercury (MeHg) toxicity humans. Here, we analyzed total Hg (T-Hg) two oceanic squid species (Ommastrephes bartramii Thysanoteuthis rhombus) an increasing commercial interest off Martini...

Organic mercury (Hg) species exert their toxicity primarily in the central nervous system. The food relevant Hg species methylmercury (MeHg) has been frequently studied regarding its neurotoxic effects in vitro and in vivo. Neurotoxicity of thiomersal, which is used as a preservative in medical preparations, is to date less characterised. Due to dealkylation of organic Hg or oxidation of elemen...

To examine the inter-species difference of sensitivity to mercury toxicity in whales, total mercury (T-Hg), methyl mercury (MeHg) and selenium (Se) levels in the liver, kidneys and muscle of three whales (common minke whales Balaenoptera acutorostrata; Bryde’s whales B. edeni; sperm whales Physeter. macrocephalus) were measured. T-Hg and MeHg were higher in the order of sperm whale > common min...

The Minamata Convention on Mercury (Hg) calls for global efforts to reduce the release and risk of Hg. A better understanding Hg budget, transformation transport as well toxicity in environment, emission controlling technologies, is important minimize pollution exposure risks. Here, we summarized recent findings regarding cycle, transport, transformation, based publications Critical Review Envi...

Toxicity of methylmercury (MeHg) to wildlife and humans results from its binding cysteine residues proteins, forming MeHg-cysteinate (MeHgCys) complexes that hinder biological functions. MeHgCys can be detoxified in vivo, yet how this occurs is unknown. We report are transformed into selenocysteinate [Hg(Sec)4] multiple animals two phyla (a waterbird, freshwater fish, earthworms) sampled differ...

Mercury (Hg) exposure is a public health concern due to its persistence in the environment and its high toxicity. Such toxicity has been associated with the generation of oxidative stress in occupationally exposed subjects, such as artisanal gold miners. In this study, we characterize occupational exposure to Hg by measuring blood, urine and hair levels, and investigate oxidative stress and DNA...

(1) Hyperglycemia leads to cytotoxicity in the heart. Although several theories are postulated for glucose toxicity-induced cardiomyocyte dysfunction, the precise mechanism still remains unclear. (2) This study was designed to evaluate the impact of elevated extracellular Ca(2+) on glucose toxicity-induced cardiac contractile and intracellular Ca(2+) anomalies as well as the mechanism(s) involv...

Although most researches with non-essential metals (NEMs) have been done with single or individual metals, in reality, organisms are often exposed to multiple contaminants at the same time through the air, food and water. In this study, we tested the toxicity of four NEMs, As, Cd, Pb, and Hg, individually and as a composite mixture using the microtox bioassay. This assay uses the reduction of b...

Mercury (Hg) contamination is receiving increased attention globally because of human health and environmental concerns. Few laboratory studies have examined the toxicity of Hg on early life stages of freshwater mussels, despite evidence that glochidia and juvenile life stages are more sensitive to contaminants than adults. Three bioassays (72-h acute glochidia, 96-h acute juvenile, and 21-d ch...

background: l1 retrotransposons are the most active mobile dna elements in human genome. unregulated l1 retrotransposition may have deleterious effect by disrupting vital genes and inducing genomic instabilities. therefore, human cells control l1 elements by silencing their activities through epigenetic mechanisms. it has been shown that cell division and heavy metals stimulate the frequency of...