Jack jumper ant (JJA) venom allergy is an important cause of anaphylaxis in south-eastern Australia. The efficacy and real-world effectiveness of JJA venom immunotherapy (VIT) to prevent anaphylaxis in allergic patients are now well established, with an evidence base that is at least equivalent to that supporting VIT for allergy to other insect species. The tolerability and safety of JJA VIT ar...

BACKGROUND Type 2 cytokine-related immune responses associated with development of antigen-specific IgE antibodies can contribute to pathology in patients with allergic diseases and to fatal anaphylaxis. However, recent findings in mice indicate that IgE also can enhance defense against honeybee venom. OBJECTIVE We tested whether IgE antibodies, IgE-dependent effector mechanisms, and a local ...

controversial immunomodulatory properties of bee venom (bv) have provided an appropriate field for more investigation. the aim of present research was to verify the effects of honeybee venom on matrix metalloproteinase activity and interferon production as well as cell proliferation in monocyte and fibroblast cell lines. the monocyte and fibroblast cell lines (k562, ht-1080, wehi-164) were used...

Bee venom is a complex mixture of proteins (enzymes and peptides) with unique pharmacological activities. The main enzymes in bee venom are hyaluronidase and phopholiphase A2. Melittin in high concentrations also has caused hemolysis of red blood cells. This study was conducted to evaluate effects of honeybee venom on hematological characteristics of albino rats. Rats were divided in 3 groups v...

Venom from different organisms was used in ancient times to treat a wide range of diseases, and combat variety enveloped non-enveloped viruses. The aim this silico research investigate the impact honeybee venom proteins peptides against Ebola virus. In current study, online offline tools were used. RaptorX (protein 3D modeling) PatchDock (protein–protein docking) as tools, while Chimera LigPlot...