Methylisothiazolinone (MI) (CAS no. 2682-20-4) and methylchloroisothiazolinone (MCI) (CAS no. 26172-55-4) have been widely used as preservatives in cosmetics, household products and industrial products since the late 1970s. The first cases of contact allergy to the MCI/MI combination were noted in 1980 (1). Ironing water is being increasing used as a product designed to making ironing more enjo...

The purpose of this review is to discuss the impact of nanocarriers administered by pulmonary route to treat and to diagnose respiratory and non respiratory diseases. Indeed, during the past 10 years, the removal of chlorofluorocarbon propellants from industrial and household products intended for the pulmonary route has lead to the developments of new alternative products. Amongst these ones, ...

BACKGROUND Methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI) and MI are common preservatives in industrial and household products and in cosmetics. Occupational contact allergy to MCI/MI or MI has been reported among painters and paint factory workers in particular. OBJECTIVES To retrospectively describe patients with occupational contact allergy to MCI/MI and MI at the Finnish Ins...

The paper reports a study into consumers’ ‘soft’ usability problems they experience using electronic household products. These problems cannot be traced back to a specification violation failure, classified as no failure found (NFF). The aim of this study is to find a relationship between consumers’ soft usability problems and their personal characteristics, encompassing demographical and cogni...

The European Union energy label, which provides information on the energy consumption of household appliances, has proven its reliability for the customers in recent years. However, a label for the product sound perception, which can be very useful for the customers but also manufacturers, is not available up to now. The energy label is required to include the sound power level of the devices. ...

Smart phones, which were once a luxury product has now become a household product. This transformation has been due to the vast amount of functionalities which a smart phone provides in just a single device. Smartphone OS, such as Android, is an Open Source mobile platform that enables us to install third party applications. Due to large amount of applications that are available on the app stor...

Among comas of toxic origin, in children, alcoholic coma due to accidental poisoning is uncommon compared with comas due to drugs or household products. It is however important to make an early diagnosis, for this is a severe from of poisoning, liable to cause irreversible cerebral lesions if not treated very quickly. It almost always causes a flask coma, without localising signs, hypothermia a...

Objective: Acute poisoning is considered as an important health problem leading to admission of children. Also, the epidemiologic surveillance specific for each country is necessary. Therefore, we conducted this study to obtain the epidemiological information on poisoning in Nemazee Hospital, a referral center in South of Iran. Methods: In this cross sectional study, we determined age, sex, pre...

Methylisothiazolinone contact allergy – are rinse-off cosmetics and household products relevant sources of exposure?* Rosella Gallo1,2, Alessio Signori3, Sonia Gervasio1,2, Silvia Riva1,2 and Aurora Parodi1,2 1 IRCCS, AOU San Martino, IST, Genoa, Italy, 2Section of Dermatology, Department of Health Sciences, University of Genoa, 16132 Genoa, Italy, and 3Section of Biostatistics, Department of H...

The Threshold of Toxicological Concern (TTC) is a level of human intake or exposure that is considered to be of negligible risk, despite the absence of chemical-specific toxicity data. The TTC approach is a form of risk characterisation in which uncertainties arising from the use of data on other compounds are balanced against the low level of exposure. The approach was initially developed by t...