نتایج جستجو برای: hscs
تعداد نتایج: 3001 فیلتر نتایج به سال:
Hematopoiesis is maintained by stem cells with the ability to both self-renew and to give rise to differentiated progeny. A proper balance between these fates is essential to prevent hematopoietic failure or uncontrolled stem cell expansion. So how do HSCs undergo self-renewal? In theory, this can occur in 2 ways; either through symmetrical cell division (SCD) where 2 new stem cells are formed,...
چکید ه سابقه و هدف استفاده از سلولهای بنیادی خونساز( HSCs )، روش استانداردی جهت درمان بسیاری از بدخیمیهای خونی و اختلالات غیرخونی محسوب میشود. خون بند ناف، دارای مزایای فراوانی نسبت به سایر منابع سلولهای بنیادی است و یکی از محدودیتهای مهم این منبع جهت پیوند, تعداد محدود سلولهای بنیادی آن میباشد. از راهکارهای پیشنهادی برای غلبه بر این مشکل، تکثیر بدون تمایز این سلولها در محیطهای ...
The cellular ontogeny of hematopoietic stem cells (HSCs) remains poorly understood because their isolation from and their identification in early developing small embryos are difficult. We attempted to dissect early developmental stages of HSCs using an in vitro mouse embryonic stem cell (ESC) differentiation system combined with inducible HOXB4 expression. Here we report the identification of ...
In this paper, the solar absorption level of PEDOT:PSS/Ge organic and inorganic hybrid cells (HSCs) with different parameters cruciform microstructure (CM) is studied, using finite-difference time domain (FDTD) method. The light in HSCs CM above 90% range 300 nm to 1300 nm. Under AM1.5 spectrum, average absorptivity energy also at a very high level. At same time, we use DEVICE software calculat...
Benzene is an occupational toxicant and an environmental pollutant that potentially causes hematotoxicity and leukemia in exposed populations. Epidemiological studies suggest an association between an increased incidence of childhood leukemia and benzene exposure during the early stages of pregnancy. However, experimental evidence supporting the association is lacking at the present time. It is...
umbilical cord blood (ucb) has been used for transplantation in the treatment of hematologic disorders as a source of hematopoietic stem cells (hscs). because of insufficient number of cord blood cd34+ cells, the expansion of these cells seems to be important for clinical application. mesenchymal stromal cells (mscs), playing an important role in hscs maintenance, were used as feeder layer. apo...
Hematopoietic stem cells (HSCs) maintain homeostasis and regenerate the blood system throughout life. It has been postulated that HSCs may be uniquely capable of preserving their genomic integrity in order to ensure lifelong function. To directly test this, we quantified DNA damage in HSCs and downstream progenitors from young and old mice, revealing that strand breaks significantly accrue in H...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید