The purpose of the study was a comparison of Oenothera paradoxa Hudziok defatted seeds extract (EPE) effect with the activity of individual constituents of the extract: pentagalloylglucose (PGG), gallic acid, (+)-catechin and the procyanidin fraction, as well as an assessment of the combined effect of EPE and vincristine (VCR) in the absence or presence of MRP1 (indomethacin) and P-glycoprotein...

Urothelial carcinoma of bladder (UCB) is a common urological malignancy in the world, but its progression mechanism remains unclear. MiR-612 was found as an anti-tumor factor multiple types cancer, while few studies have revealed functions UCB cells. Based on this, cells such HTB-9 and HTB-4, normal urothelial SV-Huc1, were used subjects this study. Western blot, qRTPCR, CCK-8 assay transwell t...

Diagnosis of cholangiocarcinoma (CCA) is difficult when patients do not show jaundice. The aim of this study was to examine the feasibility of using the total serum bile acid (TSBA) level as an aid for the diagnosis of CCA in patients without jaundice. For this purpose, TSBA of the following groups were measured using a Beckman Synchron CX4 clinical chemistry analyzer: 60 cases of CCA with tota...

PURPOSE RB94, a truncated form of RB110, has enhanced tumor suppressor potency and activity against all tumor types tested to date including bladder carcinoma. However, efficient, systemic delivery of the gene encoding RB94 specifically to tumors, is an obstacle to clinical application as an anticancer therapeutic. We have developed a systemically given, nanosized liposome DNA delivery system t...

The hexathienylbenzene-co-poly(3-hexylthiophene-2,5diyl) (HTB-co-P3HT) conducting polymer was synthesized by oxidative co-polymerization of hexathienylbenzene (HTB) and 3-hexylthiophene using iron chloride (FeCl 3 ) as an oxidant. effect chlorobenzene, toluene chloroform on the optoelectronic characteristics investigated. study revealed that spectroscopic electrochemical responses HTB-co-P3HT a...

s from the workshop, published in Reviews in Antiviral Therapy & Infectious Diseases 2011_3 are available to download from the meeting website. http://www.virology-education.com/index.cfm/t/Workshop_Materials/vid/34792068-01CF-4196-986A8271C014BBD7 Selected presentations are also available online. http://regist2.virology-education.com/2011/12HIV_PK/13_April.html Articles included in this issue ...

Astrocytomas are tumors which arise from astrocytes, cells that form the blood-brain barrier. There are very few drugs that successfully treat brain tumors. In this study, the cytotoxic effects on the HTB-12 astrocytoma cell line by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) were studied. The presence of the TRAIL receptors, Death receptor 4 (DR4) and Death receptor 5 (DR5)...

Chronic pelvic pain (HTB) remains a relevant multidisciplinary problem. Its symptoms are the result of interaction between psychological factors and dysfunction immune, neurological endocrine systems. HTB is serious problem for women. Approximately 14% women experienced at least once in their lives. grueling related to significant costs incidence, its etiology multifactorial, which often compli...

The purpose of this study was to investigate the relationship between birth weight and appetite related hormones, insulin resistance, and antioxidant status in overweight children aged 9-10 years. Thirty-four healthy overweight children (18 boys, 16 girls) were evaluated with respect to anthropometric measurement, lipid profiles, leptin, ghrelin, glucose, insulin, C-peptide, lipid soluble vitam...