introduction: acquired immunodeficiency syndrome (aids) is a worldwide infection. because of the vast array of manifestations of aids and its many atypical presentations, it is becoming increasingly challenging for clinicians to accurately diagnose new lesions. materials and methods: in a descriptive cross-sectional study conducted from 2007 to 2010, 50 patients with a proven human immunodefici...

Background: Hemophilia A and B are the most frequent congenital coagulation disorders. This study was conducted to determine the prevalence of hepatitis B, C and human immunodeficiency viruses among hemophilic patients in Hamadan, Iran. Patients and Methods: In this study, patients with hemophilia A and B treated in Hamedan Hemophilia Center, Hamedan, Iran, were screened for hepatitis B, C and...

Human immunodeficiency virus infection / acquired immunodeficiency syndrome (HIV/AIDS) is a disease pertained to the human immune system. Given its crucial role in viral replication, HIV-1 protease (HIV-1 PR) is a prime therapeutic target in AIDS therapy. In this regard, the dynamic aspects of ligand-enzyme interactions may indicate an important role of conformational variability in HIV-1 PR in...

Background: Scleroderma is a chronic systemic disorder that affects the connective tissues. It is characterized by several immune manifestations, inflammation, vascular damage, and fibrosis. Some of the viral infections with complex mechanisms are involved in the development and progression of many autoimmune diseases, such as scleroderma. The present study aimed to investigate the serological ...

Human immunodeficiency virus (HIV) infection has been associated with cardiac disease, including anatomical or functional disturbance to the heart. Cardiomyopathy (CMP) is one of these disturbances that have been associated with high rates of morbidity and mortality. In this review article, several aspects of potential relationships between HIV infection and cardiomyopathy development have been...

Human immunodeficiency virus (HIV) rapid variant mutations challenges diagnostic assays. Our variant-tolerant isothermal nucleic acid based amplification technique enables reliable detection at the point-of-care.

Introduction: Southeast Asia is the second continent that has a higher population of Human Immunodeficiency Virus (HIV) infection. Indonesia needs to be vigilant prevent spreading and transmission this virus. One services provided by government for initial screening HIV/ AIDS Voluntary Counseling Testing (VCT). This research aimed identify behavior factors related utilization VCT Man who Sex wi...

unfortunately, we do not know how many perinatally (human immunodeficiency virus) hiv-infected pepole are living in contries today, while knowing these informations is necessary. unaids reports that there are 3.4 million children under 15 years of age with hiv and 2 million adolescents between 10 and 19 years of age. although the vast majority of children were perinatally infected, older childr...

Human immunodeficiency virus type 1 (HIV-1) is most notable for its role in directly infecting and killing CD4 T cells the immune system, which can lead to acquisition of Acquired Immunodeficiency Syndrome (AIDS). Currently, there are no cures HIV-1, leaving 37 million people with HIV-1 infections definitive treatment. Researchers working towards developing long-term treatments using CRISPR-Cas...

Abstract Background Thalassemia patients that are conventionally treated by a regular transfusion regimen are exposed to blood born viral infections.The aim of this study was to investigate the seroprevalence of hepatitis B virus (HBV), hepatitis C virus (HCV) , and human Immunodeficiency virus(HIV) among all multitransfused thalassemia patients in west north of Iran. Material and methods A...