نتایج جستجو برای: hutchinson
تعداد نتایج: 1886 فیلتر نتایج به سال:
Progeria is a human disease model of accelerated ageing. The progeria syndrome is a rare genetic disorder, first reported in 1886 by Hutchinson and Guilford in England. The inheritance pattern, paternal age eVect, and lack of consanguinity argue that it is due to a sporadic dominant mutation. HutchinsonGuilford progeria syndrome (HGPS) is associated with several features of premature ageing—for...
Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare, uniformly fatal, segmental "premature aging" disease in which children exhibit phenotypes that may give us insights into the aging process at both the cellular and organismal levels. Initial presentation in early childhood is primarily based on growth and dermatologic findings. Primary morbidity and mortality for children with HG...
The study is an analysis of the character Tessie Hutchinson in American writer Shirley Jackson’s short story The Lottery. The duality in Tessie’s character represents the psychological conditions of all the participants in the lottery; while at the same time, having unfortunately won the lottery, Mrs. Hutchingson serves in the story as a victim, a scapegoat of the brutal primitive ceremony. In ...
Hutchinson-Gilford progeria syndrome is an extremely rare condition with features of premature and accelerated aging. The pattern of inheritance is unclear, although autosomal dominant mutations have been proposed. The disease presentation is usually in infancy and early childhood with a characteristic phenotype of short stature, abnormal skin and nail, beaked nose, loss of subcutaneous f...
University of Arizona Cancer Center, University of Arizona, Tucson, AZ; SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, WA; Department of Pathology, University of Arizona, Tucson, AZ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; James P. Wilmot Cancer Center, University of Rochester, Rochester, NY; Loyola University Medical Center, M...
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