background and objectives: datura innoxiamilleris one of the two species of datura (solanaceae) which grow in iran. there are many reports of the biological activities of datura and in the present study the ability of datura innoxia for inhibiting angiogenesis was evaluated. methods: the methanol extract and petroleum ether, chloroform and methanol fractions of datura innoxia flowers were obtai...

Background/Aim. A substantial line of evidence indicates that Kv4.2 and Kv4.3 channels are the major components rapid transient-outward potassium currents (A-type cur-rents). It is speculated those may be involved in maintenance membrane potential, as well regulation propagation frequency action potentials. However, very little known about presence function A-type human vascular smooth muscles ...

Platelets regulate new blood vessel growth, because they contain a number of angiogenesis promoters and inhibitors. Additionally, platelets contain matrix metalloproteinases (MMPs), which when released mediate platelet adhesion and aggregation, and plasminogen, a fibrinolytic system enzyme that serves to limit blood clot formation. Enzymatic cleavage of plasminogen by MMPs generates angiostatin...

The hitting time, huv , of a random walk on a finite graph G, is the expected time for the walk to reach vertex v given that it started at vertex u. We present two methods of calculating the hitting time between vertices of finite graphs, along with applications to specific classes of graphs, including grids, trees, and the ’tadpole’ graphs. keywords: random walks, hitting time

Many indoor places, including aged classrooms and offices, prisons, homeless shelters, etc., are poorly ventilated but resource-limited to afford expensive ventilation upgrades or commercial air purification systems, raising concerns on the safety of opening activities in these places era COVID-19 pandemic. To address this challenge, using computational fluid dynamics, we conducted a systematic...

OBJECTIVE To know the epidemiology of Acute Kidney Injury (AKI) in the pediatric population at Hospital Universitario del Valle (HUV), a tertiary University Hospital in Cali, Colombia. METHODS We obtained a series of cases through daily surveillance for a seven-month period (June 1 to December 31, 2009) in patients older than 30 days and under 18 years at HUV. We excluded patients with previo...

Platelets regulate new blood vessel growth, because they contain a number of angiogenesis promoters and inhibitors. Additionally, platelets contain matrix metalloproteinases (MMPs), which when released mediate platelet adhesion and aggregation, and plasminogen, a fibrinolytic system enzyme that serves to limit blood clot formation. Enzymatic cleavage of plasminogen by MMPs generates angiostatin...

Background and objectives: Angiogenesis is essential for tumor survival. Inhibiting angiogenesis could be a mechanism for hindering tumor development. Numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. In the present study, Crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesi...

Background and objectives: Datura innoxiaMilleris one of the two species of Datura (Solanaceae) which grow in Iran. There are many reports of the biological activities of Datura and in the present study the ability of Datura innoxia for inhibiting angiogenesis was evaluated. Methods: The methanol extract and petroleum ether, ...