The directly compressible floating-bioadhesive tablets of tramadol were formulated using varying amounts Carbopol 971P (CP) and hydroxy-propylmethyl cellulose (HPMC), along with other requisite excipients. In vitro drug release profile, floatational characteristics and ex vivo bioadhesive strength using texture analyzer were determined, and systematically optimized using a 3(2) central composit...

The gastroretentive dosage form of famotidine was modified using tamarind seed powders to prolong the gastric retention time. Tamarind seeds were used in two different forms having different swelling and gelling properties: with husk (TSP) or without husk (TKP). TKP (TKP1 to TKP 6) and TSP (TSP1 to TSP 6) series were prepared using tamarind powder:xanthan in the ratios of 5:0, 4:1, 3:2, 2:3, 1:...

The purpose of this study is to evaluate the in vitro and in vivo performance of gastro-retentive matrix tablets having Metformin HCl as model drug and combination of natural polymers. A total of 16 formulations were prepared by a wet granulation method using xanthan, tamarind seed powder, tamarind kernel powder and salep as the gel-forming agents and sodium bicarbonate as a gas-forming agent. ...

When micron-sized particles are trapped in a linear periodic array, for example, by using optical tweezers, they interact only through the hydrodynamic forces between them. This couples the motion of the spheres and it has been predicted that an extended system might behave as an elastic medium that could support underdamped propagating waves. In practice, these underdamped modes can be observe...

The main objective of the present study was to formulate gastroretentive effervescent sustained release drug delivery systems of risperidone floating tablets with the help of Methocel® K15, Ethocel® standard 7FP premium, Eudragit ® RS100 sustained release polymers to improve its safety profile, bioavailability and patient compliance. Risperidone floating tablets were formulated by wet granulati...

The first measurement of the elliptic transverse flow for multi-strange baryons Ξ and Ω in high energy heavy ion collisions is presented, which may indicate the presence of partonic collectivity. A hydrodynamically inspired model fit to the transverse momentum spectra and elliptic flow of Ξand Ξ + indicates that these particles might be emitted from the system at a high temperature (∼ 150 MeV) ...

using the group inverse, an explicit solution to a symmetric singular system is described. The general explicit solution is derived when the symmetric singular system satisfies the regularity condition. Certain special properties of these singular systems are presented. Finally, a symmetric balanced realization is obtained from an equivalent standard control system. @ 2002 Elsevier Science Ltd....

Hydrodynamically confined flow device technology is a young research area with high practical application potential in surface processing, assay development, and in various areas of single cell research. Several variants have been developed, and most recently, theoretical and conceptual studies, as well as fully developed automated systems, were presented. In this article we review concepts, fa...