Wharton’s jelly mesenchymal stem cells (HWJMSCs) hold promise for myocardial regeneration, but optimal treatment regimen (preferably with a growth factor) is required to maximize functional benefits. The aim of this study was to explore the cardioprotective and angiogenesis effects of HWJMSCs combined with insulin-like growth factor-1 (IGF-1) in the treatment of acute myocardial infarction. Th...

A novel pH-responsive superabsorbent hydrogel based on gelatin was prepared through crosslinking copolymerization of poly (acrylic acid) and poly (itaconic acid). The copolymerization conditions including monomers, initiator, gelatin and crosslinker concentration, reaction temperature, and neutralization percent were systematically optimized to achieve a hydrogel with swelling capacity as high ...

Methylglyoxal (MGO) is a toxic, dicarbonyl metabolite in all living cells and its detoxification is regulated by glyoxalase I (GLOI). Herein, we rationally designed a precursor o-phenylenediamine-Phe-Phe-OH (1) which “click” reacts with MGO to yield amphiphilic methylquinoxaline-Phe-Phe-OH (2) to self-assemble into supramolecular hydrogel II (Gel II). Cryo-TEM images of Gel II suggested that th...

PURPOSE The purpose of this study is to compare the adhesion capabilities of the most important etiologic agents of microbial ocular infection to the recently available silicone-hydrogel lenses with those to a conventional hydrogel lens. METHODS In vitro static adhesion assays of Pseudomonas aeruginosa 10,145, Staphylococcus epidermidis 9142 (biofilm-positive), and 12,228 (biofilm-negative) t...

abstract turf grass as a main grown cover plant has a unique place in green space planning. in order to study the effect of hydrogel and paclobutrazol on water requirement of turfgrasse (lolium perenne l. barbal) a factorial experiment based on a brcd with 3 replication was conducted in the summer of 2010 in mashhad. the factors under study were 4 levels of hydrogel (0, 3, 6, 9 gr/kg soil), 3 l...

A G-rich nucleic acid-tethered acrylamide/N-isopropylacrylamide (NIPAM) copolymer is prepared. The nucleic acid-modified pNIPAM chains assemble, in the presence of K ions, into a stimuli-responsive G-quadruplex-crosslinked pNIPAM hydrogel undergoing cyclic and reversible solution/hydrogel/solid transitions. Addition of kryptofix [2.2.2], CP, to the K-stabilized G-quadruplex-crosslinked hydrogel...

Purpose. To evaluate the feasibility of regional radiochemotherapy of mammary tumors using in situ hydrogel loaded with cisplatin (CDDP) and rhenium-188 (Re). Methods. Sodium alginate (SA) and calcium chloride were used to create a hydrogel for delivery of CDDP and Re. In vitro studies were performed to evaluate cytotoxic effects of Re-hydrogel and sustained-release ability of the CDDP-hydrogel...

a key parameter for the application of polymer gels in water shut off treatment is the adsorption of polymer gel onto the rock surface. so, the adsorption properties of a nanocomposite hydrogel were discussed in this research by crosslinking of sulfonated polyacrylamide/sodium montmorillonite aqueous solutions with chromium triacetate. the x-ray diffraction patterns indicated that exfoliated ty...

Abstract Hydrogel-like structures are responsible for the low friction experienced by our joints when we walk or eyelids blink. At loads, hydrogel contacts show extremely that rises with velocity beyond a threshold speed. Here combine mesoscopic simulations and experiments to test polymer-relaxation hypothesis this dependence, where velocity-dependent regime emerges perturbation of interfacial ...

background: sustained release delivery system can reduce the dosage frequency and maintain the therapeutic level of drugs for a longer time. biodegradable, biocompatible and thermosensitive chitosan-beta-glycerophosphate (c-gp) solutions can solidify at body temperature and maintain their physical integrity for a longer duration. objectives: to develop a novel delivery system based on the integ...