نتایج جستجو برای: hydrogenbond

تعداد نتایج: 22  

2013
Amir Eldar Haim Rozenberg Yael Diskin-Posner Remo Rohs

A p53 hot-spot mutation found frequently in human cancer is the replacement of R273 by histidine or cysteine residues resulting in p53 loss of function as a tumor suppressor. These mutants can be reactivated by the incorporation of second-site suppressor mutations. Here, we present high-resolution crystal structures of the p53 core domains of the cancer-related proteins, the rescued proteins an...

2014
Jian Lü Cristina Perez-Krap Mikhail Suyetin Nada H. Alsmail Yong Yan Sihai Yang William Lewis Elena Bichoutskaia Chiu C. Tang Alexander J. Blake Rong Cao Martin Schröder

A robust binary hydrogen-bonded supramolecular organic framework (SOF-7) has been synthesized by solvothermal reaction of 1,4-bis-(4-(3,5-dicyano2,6-dipyridyl)dihydropyridyl)benzene (1) and 5,5′-bis(azanediyl)-oxalyl-diisophthalic acid (2). Single crystal Xray diffraction analysis shows that SOF-7 comprises 2 and 1,4-bis-(4-(3,5-dicyano-2,6-dipyridyl)pyridyl)benzene (3); the latter formed in si...

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