A hydrophilic matrix tablet is the simplest and most cost-effective method of fabricating an extended release (ER) solid oral dosage form. The majority of commercially available matrix formulations are in the form of tablets, and their method of manufacture is similar to conventional tablet formulations: granulation, blending, compression and coating. In its simplest form, a typical ER matrix f...

the purpose of this work was to develop once daily sustained release (sr) matrix tablets of naproxen, an anti-inflammatory agent. the tablets were prepared by wet granulation method along with hydrophilic matrix materials like methocel k 15m cr and methocel k 100m cr. the granules were evaluated for bulk density, angle of repose, compressibility index, total porosity and drug content. the table...

Assimilating hydrophilic hollow polymer spheres (HPS) into Nafion matrix by a loading of 0.5 wt % led to a restructured hydrophilic channel, composed of the pendant sulfonic acid groups (–SO3H) and the imbedded hydrophilic hollow spheres. The tiny hydrophilic hollow chamber was critical to retaining moisture and facilitating proton transfer in the composite membranes. To obtain such a tiny cavi...

Lignocellulosic natural fibres are hydrophilic, while many matrix systems for composites hydrophobic. The achievement of good mechanical properties fibre-reinforced polymer (NFRP) relies on fibre-to-matrix bonding at the interface. reinforcement is normally coated with an amphiphilic coupling agent to promote a strong A novel alternative approach dissolve in hardener resin before creating stoic...

The objective of present work is to develop and characterize an oral sustained release matrix tablet of complexedNicardipine Hydrochloride by employing hydrophilic and hydrophilic polymers. Due to poor water solubility of the drug its bioavailability is dissolution rate limited. The purpose of the study was to increase the solubility of Nicardipine by cyclodextrin inclusion complex technique. C...

A micellar cubic LC phase consisting of a hydrophilic matrix exhibited enhanced ionic transport and mechanical properties without macroscopic orientation, which are attributed to the non-tortuous ionic transport and highly symmetric cubic lattice, respectively.