Hydroquinone (HQ, 1,4-benzenediol) is a hydroxylated benzene metabolite with various biological activities, including anti-oxidative, neuroprotective, immunomodulatory, and anti-inflammatory functions. However, the anti-cancer activity of HQ is not well understood. In this study, the in vitro and in vivo anti-cancer activity of HQ was investigated in various cancer cells and tumor-bearing mouse...

Background Melasma is a difficult-to-treat hyperpigmentary disorder. Ablative fractional laser (AFL)-assisted delivery of topically applied drugs to varied targets in the skin has been an area of ongoing study and research. Objective The objective of this study was to evaluate the efficacy and safety of fractional erbium-doped yttrium aluminum garnet (Er:YAG) laser as an assisted drug deliver...

Background Hydroquinone (HQ) is frequently combined with retinoic acid (RA) to enhance lightening efficacy, which may also affect skin irritancy. Although skin irritation leads to postinflammatory hyperpigmentation, little research has been performed to compare skin irritancy between each component and the combination. Objective This study was done to examine whether HQ-RA combination increas...

Hydroquinone (HQ) was electrochemically measured using convolutive cyclic voltammetry and differential pulse (DPV) on a nano-architecture mesoporous platinum film grown from hexagonal liquid crystalline template of C16EO8 surfactant in 1.0 mol/l HClO4. The HQ voltammograms produced one oxidative peak the forward sweep potential reductive reverse sweep. effect concentration investigated differen...

The formation of hydroquinone (HQ) clathrate and the guest behaviors binary (CH4 + CO2) gas mixtures were investigated by focusing on an application to separate CO2 from landfill gases. Spectroscopic measurements show that at two experimental pressures 20 40 bar, molecules are preferentially captured in HQ clathrates regardless composition. In addition, preferential occupation is observed more ...

A running colour electrophoresis of protein in sodium dodecylsulfate (SDS)-polyacrylamide gel (PAG) has been developed and the coloured gel was restained with silver nitrate and hydroquinone (HQ) within 20min. Trichloroacetic acid (TCA) was found to be a powerful destaining reagent and reproducibility of this double staining procedure was excellent.

Excilamps are new UV sources with great potential for application in wastewater treatment. In the present work, a XeBr excilamp emitting radiation at 283 nm has been used for the photodegradation of 4-chlorophenol within a range of concentrations from 50 to 500 mg L. Total removal of 4-chlorophenol was achieved for all concentrations assayed. The two main photoproduct intermediates formed along...

Werner syndrome (WS) is a rare autosomal progeroid disorder caused by a mutation in the gene encoding the WRN (Werner syndrome protein), a member of the RecQ family of helicases with a role in maintaining genomic stability. Genetic association studies have previously suggested a link between WRN and susceptibility to benzene-induced hematotoxicity. To further explore the role of WRN in benzene-...

NAD(P)H:quinone oxidoreductase 1 (NQO1) is a two-electron reductase that detoxifies quinones derived from the oxidation of phenolic metabolites of benzene. A polymorphism in NQO1, a C609T substitution, has been identified, and individuals homozygous for this change (T/T) have no detectable NQO1. Exposed workers with a T/T genotype have an increased risk of benzene hematotoxicity. This finding s...

Previous studies have demonstrated the role of hydroquinone (HQ), a hydroxylated benzene metabolite, in modulating various immune responses; however, its role in macrophage-mediated inflammatory responses is not fully understood. In this study, the role of HQ in inflammatory responses and the underlying molecular mechanism were explored in macrophages. HQ down-regulated the expression of interf...