A 36-year-old male with mild Ebstein's anomaly developed severe right-sided heart failure, following a 5-year-long course of hypereosinophilic syndrome. No regular followups had been done, during the years of antineoplastic therapy. A year after being cured from the hypereosinophilic syndrome, the patient developed right-sided heart failure symptoms and was found to have excessive fibrosis of t...

Important cardiac manifestations in the idiopathic hypereosinophilic syndrome include mitral regurgitation and peripheral embolization. To determine the anatomic basis of these abnormalities, real-time, wide-angle, two-dimensional echocardiography (2-D echo) was performed in 21 patients with the hypereosinophilic syndrome. Nine patients (43%) had clinical evidence of mitral regurgitation, and e...

characterized by prominent peripheral eosinophilic leukocytosis without an identifiable cause (1, 2). Eosinophilic infiltration occurs in various systems and organs such as the nervous system, heart, hematopoietic system, liver, spleen, bowel and lung. The diagnostic criteria of idiopathic hypereosinophilic syndrome includes peripheral eosinophilia of more than 1500 eosinophils/mm for more than...

Heterogeneity of human peripheral blood eosinophils: IHS is the cardiac involvement (15). A restrictive type variability in cell density and cytotoxic ability in relation of cardiomyopathy such as endomyocardial Ž brosis is to the level and the origin of hypereosinophilia. Int Arch characteristic (16). Moreover, IHS can also present with Allergy Appl Immunol 1983; 72: 336–346. a dilated cardiom...