random samples from asymptomatic leaves and branches of five native medicinal plants: stachys lavandulifolia, rumex pulcher, hypericum scabrum, starja bachteriarica and achillea kellalensis were collected from chaharmahal province of iran and examined for the presence of endophytic bacteria and fungi with biological activity. from 8 isolated endophytic fungi, all displayed considerable activity...

this study demonstrates the changes in six different pathophysiological parameters such as body weight, body temperature, fecal pellet count, blood-brain barrier (bbb) permeability, plasma corticosterone level and emergence of hemorrhagic peptic ulcer spots due to exposure to high environmental heat in three different age groups of freely moving rats. methods: each age group of rats was sub div...

The widely-used Chinese medicinal herb Hypericum japonicum, also known as Hypericum japonicum Thunb or Tianjihuang, displays potent anti‑carcinogenic effects against liver cancer. However, the molecular mechanism underlying the therapeutic effects of Hypericum japonicum remains to be elucidated. The present study investigated the in vivo efficacy of ethyl acetate extract of Hypericum japonicum ...

BACKGROUND AND OBJECTIVE: Pulmonary fibrosis is a chronic interstitial lung disease caused by parenchymal lung damage due to inflammatory factors and fibrosis. Hypericum perforatum contains various flavonoids with antioxidant properties. This study aimed to evaluate protective effects of hydroalcoholic extract of Hypericum against bleomycin-induced pulmonary fibrosis in rats. METHODS: This empi...

Bu çalışmada, önemli tıbbi ve aromatik bitki olan Hypericum türlerinin Rhizoctonia solani üzerine antifungal aktivitesi incelenmiştir. (H. heterophyllum, H. scabrum perforatum) çiçek, gövde yapraklarının bazı çözücülerdeki (metanol, etanol, aseton kloroform) ekstraktlarının %2’lik konsantrasyonu solani’ye karşı test edilmiştir. Ekstraktların aktiviteleri bu patojen ile mücadelede kullanılan sen...

BACKGROUND/OBJECTIVES This study was conducted to assess the potential of St. John's Wort (Hypericum perforatum) to prevent obesity and abnormalities in lipid metabolism induced by ovariectomy in a rat model without stimulatory activity on uterus. MATERIALS/METHODS Ovariectomized (OVX) rats were treated for 6 weeks with 70% ethanol extracts of Hypericum perforatum [HPEs: whole plant (WHPE) an...

Facilitation or competition occurs among plant species when one alter ameliorates the environment for another needs same sources of species. The objective this study was to determine facilitative competitive effect on Bromus variegatus, Festuca ovina, Koeleria cristata growing with isolated, Medicago papillosa, Astragalus microcephalus, Thymus parviflorus, and Hypericum scabrum, arranged in com...