Infantile hypertrophic pyloric stenosis is a common condition affecting young infants; despite its frequency, it has been recognized only for a little over a century, and its etiology remains unknown. Nevertheless, understanding of the condition and of effective treatment have undergone a remarkable evolution in the 20th century, reducing the mortality rate from over 50% to nearly 0%. The lesio...

In the last few years the author has treated forty consecutive cases of hypertrophic pyloric stenosis with eumydfin (atropine methyl nitrate), which was brought to the notice of paediatricians in this country by Svensgaard in 1935. The analysis of this series has brought out certain points, which, had the writer realized them in time, would have improved the results. These factors are here disc...

Plasma concentrations of gastrin, somatostatin, neurotensin, and enteroglucagon were measured by radioimmunoassay in normal 30and 45-day-old neonates and age-matched infants with confirmed idiopathic hypertrophic pyloric stenosis. Plasma gastrin and somatostatin concentrations were similar in both groups, whereas neurotensin and enteroglucagon were significantly lower in the pyloric stenosis gr...

A 22 year old male presented with symptoms of gastric outlet obstruction. Endoscopy showed a hypertrophic nodular lesion around the pyloric opening with pyloric stenosis. The endoscopic biopsy and histopathological examination revealed tuberculosis involving the stomach, an extremely rare lesion.

Gastric biopsies from 35 infants with hypertrophic pyloric stenosis have been assessed for histological features of gastritis. No erosions were found, and there was no excess cellular infiltration of the lamina propria compared with a control group. Fresh haemorrhage into the lamina propria was frequent in both pyloric stenosis and control sections.