BACKGROUND Total thyroidectomy (TT) is a commonly performed surgery and postoperative hypocalcemia is a major detriment to early discharge. The aim of this randomized controlled trial was to ascertain the usefulness of routine pre- and post-operative calcium and Vitamin D supplementation in prevention of hypocalcemia after TT. MATERIALS AND METHODS Sixty consecutive patients who underwent tot...

OBJECTIVE The incidence of and risk factors for hypocalcemia following thyroidectomy were evaluated in this study. MATERIAL AND METHODS One hundred and ninety thyroidectomy patients were evaluated retrospectively for factors that might contribute to postoperative hypocalcemia; age, hyperthyroidism, malignancy, the extent of surgery (total/near total/subtotal thyroidectomy), cervical lymph nod...

considering the fact that early hypocalcemia is the most common type of neonatal hypocalcemia which manifests during the first few days of iife (72 hours) and that hypocalcemia in low birth weight neonates is very common, this descriptive study on hypocalcemia was conducted to determine the frequency of hypocalcemia in low birth weight neonates in the city of kashan in the first 9 months of the...

the main objective of this study was to identify the incidence of post-thyroidectomy hypocalcemia in patients underwent lobectomy, subtotal thyroidectomy or total thyroidectomy. this randomized trial study was performed from may 2010 to july 2011 among 108 consecutive patients undergoing thyroidectomy. patients were allocated into 3 groups based on the 3 common type of thyroidectomy. pre and po...

OBJECTIVE Thyroidectomy is the most common cause of hypocalcemia. Preservation of parathyroid glands in situ is essential in preventing this complication. The aims of our study were to review patients who underwent parathyroid gland autotransplantation during thyroidectomy, and to compare hypocalcemia rates in patients with and without autotransplantation. MATERIAL AND METHODS Parathyroid gla...

Objective: This study was designed to determine whether or not "hypocalcemia following complete thyroidectomy in hyperthyroid patients associated with preoperative vitamin D insufficiency." Methodology: research carried out the West Surgical Ward of Mayo Hospital Lahore, Pakistan. Total 60 were included study. Patients divided two groups i.e. Vit-D deficient group “with deficiency” and sufficie...

PURPOSE To describe the clinical characteristics of full-term neonates with hypocalcemia and to suggest factors associated with neonatal hypocalcemia. METHODS The medical records of full-term neonates with hypocalcemia were reviewed. Hypocalcemia was defined as an ionized calcium (iCa) concentration of <4 mg/dL. Parathyroid hormone (PTH) insufficiency was defined as a serum PTH level of <60 p...

Denosumab, a fully human monoclonal antibody that inhibits the receptor activator of nuclear factor-κB ligand, inhibits the activation of osteoclasts. Some clinical trials have shown that denosumab suppresses bone resorption in patients with advanced cancer, but hypocalcemia has been reported as a serious adverse effect after the administration of denosumab. It is difficult to predict hypocalce...

The stimulation of parathyroid hormone (PTH) secretion by hypocalcemia is reduced when hypocalcemia is preceded by hypercalcemia. The present study investigates whether the duration and degree of hypercalcemia influence the reduced PTH response to hypocalcemia after hypercalcemia. In addition, the implication of the arachidonic acid (AA) signaling pathway in this effect is evaluated. The PTH re...

BACKGROUND The most common complication which occurs after thyroidectomy is postoperative hypocalcemia due to parathyroid gland damage. It usually appears 24-48 hours postoperatively, but there are clinical and biochemical factors which may contribute to its earlier diagnosis. OBJECTIVES The aim of this study was to assess clinical and biochemical factors which can influence postoperative hyp...