Congenitally missing teeth, or hypodontia, is one of the most common abnormalities of the human dentition and has a critical and often lifelong impact on the oral health of affected individuals. Here we review hypodontia and describe the patterns of inheritance it can display. A short review of tooth development and a primer in human genetics are presented. Approaches used to determine the unde...

INTRODUCTION This study was performed to examine craniofacial structures in persons with hypodontia and to reveal any differences, that may occur, when agenetic teeth are only found in the maxilla, the mandible or in both jaws. The groups consistent of 50 children (33 girls, 17 boys) aged between 9 and 13.5 years were analyzed and assigned to three subgroups. Group 1 = upper jaw hypodontia. Gro...

Tooth development is regulated by a reciprocal series of epithelial-mesenchymal interactions. With the large number of genes involved in the odontogenesis process, the opportunity for mutations to disrupt this process is high. Mutational analysis has revealed genes that are major causes of non-syndromic hypodontia. The most common permanent missing teeth are the third molars, second premolars, ...

Although hypodontia, or oligodontia, is one of the most common human dental anomalies observed, there have been few studies on the association of other anomalies occurring with it. The present investigation of 1032 patient records found that 65.7% of patients with hypodontia showed ankylosis of primary molars compared to only 1.5% of control children (P less than 0.001). In addition, taurodonti...

BACKGROUND AND AIMS Hypodontia is a common developmental abnormality of dentition. This study aimed to determine tooth width in patients affected with mild hypodontia and compare the results with a control group without tooth agenesis. MATERIALS AND METHODS The orthodontic records of 25 patients with congenital missing of one or two teeth (hypodontia group), and 25 subjects with full dentitio...

Hypodontia is the congenital absence of one or more teeth and may affect permanent teeth. Several options are indicated to treat hypodontia, including the maintenance of primary teeth or space redistribution for restorative treatment with partial adhesive bridges, tooth transplantation, and implants. However, a multidisciplinary approach is the most important requirement for the ideal treatment...

Address correspondence to: Augusto R. Elías-Boneta, DMD, MSD, Assistant Dean of Research, School of Dental Medicine, University of Puerto Rico Medical Sciences Campus, PO Box 365067, San Juan, PR 00936-5067. Email: [email protected] Objective: To estimate the prevalence of hypodontia in a group of 10to 14-yearolds from a group of orthodontic clinics in Puerto Rico. Methods: A cross-sectiona...

Hypodontia, or tooth agenesis, is the most prevalent craniofacial malformation in humans. It may occur as part of a recognised genetic syndrome or as a nonsyndromic isolated trait. Excluding third molars, the reported prevalence of hypodontia ranges from 1.6 to 6.9%, depending on the population studied. Most affected individuals lack only one or two teeth, with permanent second premolars and up...

The frequency of carriers of X linked hypohidrotic ectodermal dysplasia among females with hypodontia of the permanent dentition (excluding third molars) could be as high as 1 in 500, and among females with deciduous hypodontia could be as high as 1 in 50. Since it may be possible to identify carriers form among female hypodontia cases in general by virtue of a reduced sweat pore count, the pot...