The electronic spectroscopy and photodissociation dynamics of the I3 radical are investigated with two experimental methods. The ground and several low-lying excited states of the I3 radical are characterized by photoelectron spectroscopy of I3 2 at 213 nm. Assignments of these states are discussed with reference to recent calculations. In addition, photodissociation of the I3 radical was inves...

Allocation of research funding, as well as promotion and tenure decisions, are increasingly made using indicators and impact factors drawn from citations to published work. A debate among scientometricians about proper normalization of citation counts has resolved with the creation of an Integrated Impact Indicator (I3) that solves a number of problems found among previously used indicators. Th...

Muscarinic M2, M4, and M2-M4 chimera receptors were transiently expressed in HEK-293 tsA201 cells, and agonist-dependent internalization of these receptors and recycling of internalized receptors were examined by measuring the amount of cell-surface receptors as [3H]N-methylscopolamine (NMS) binding activity. Coexpression of a dominant negative form of dynamin (DN-dynamin,dynamin K44A) greatly ...

Understanding the precise structure and function of the intracellular domains of G protein-coupled receptors is essential for understanding how receptors are regulated, and how they transduce their signals from the extracellular milieu to intracellular sites. To understand better the structure and function of the intracellular domain of the 5-hydroxytryptamine2A (5-HT2A) receptor, a model G(alp...

This study aims at investigating the acoustic correlates of supralaryngeal and muscular tension voice quality settings (VQS). Speech samples from 40 speakers were perceptually analyzed by means of the Vocal Profile Analysis Scheme (VPAS). Acoustic analysis comprised formant frequency (F1, F2 and F3) and intensity measurements (I1, I2 and I3) of seven Brazilian Portuguese vowels. Multivariate st...

Heterotrimeric G proteins of the Gα(i) family have been implicated in signaling pathways regulating cell migration in immune diseases. The Gα(i)-protein-coupled C5a receptor is a critical regulator of IgG FcR function in experimental models of immune complex (IC)-induced inflammation. By using mice deficient for Gα(i2) or Gα(i3), we show that Gα(i2) is necessary for neutrophil influx in skin an...

Universities are undertaking transformation projects that align their work with the Sustainable Development Goals. This paper describes how Ocean I3, an educational innovation project aims to reduce plastic in sea, has made impact on its community over three editions (2018/19 2020/21). Methodologically, it been approached by people who make up technical team and academic coordination as explora...

Methods and results Male C57BL/6 mice (n=30) were immunized with 100μg of peanut protein. Half received a 30-day raw-peanutchallenge-diet (CD) (inflamed-I) while the other received mouse chow (controls-C)(Teixeira 2008). They were further divided and received sweetened OVA (new protein) (egg white diluted in distilled H2O, 1:5 v/v+5% sucralose) orally for 7 days, on day 0 (I1 C1), 10 (I2 C2) or...