Rho family GTPases act as molecular switches to regulate a range of physiological functions, including the regulation of the actin-based cytoskeleton, membrane trafficking, cell morphology, nuclear gene expression, and cell growth. Rho function is regulated by its ability to bind GTP and by its localization. We previously demonstrated functional and physical interactions between Rho3 and the cl...

We predict by first-principles methods a phase transition in TiO2 at 6.5 Mbar from the Fe2P-type polymorph to a ten-coordinated structure with space group I4/mmm. This is the first report, to our knowledge, of the pressure-induced phase transition to the I4/mmm structure among all dioxide compounds. The I4/mmm structure was found to be up to 3.3% denser across all pressures investigated. Signif...

We predict by first-principles methods a phase transition in TiO2 at 6.5 Mbar from the Fe2P-type polymorph to a ten-coordinated structure with space group I4/mmm. This is the first report of the pressure-induced phase transition to the I4/mmm structure amongst all dioxide compounds. The I4/mmm structure was found to be up to 3.3% denser across all pressures investigated. Significant differences...

sustainable economical production of tea depends on the proper use of water and fertilizer. for this purpose, the role of supplemental irrigation and nitrogen fertilizer on economical production of tea plantations was studied by assessment of yield, production function, water use efficiency, and benefit/cost ratio, and final return in a field experiment at feshalam tea research station in fouma...

Background and Objectives: Extended-pulse dye lasers (EPDL) are commonly used to treat a variety of vascular lesions. This study evaluated whether differences in pulse formats and cooling methods might affect outcome in the treatment of small facial telangictasia. Study Design/Materials and Methods: Ten subjects presenting with symmetric, bilateral facial telangiectasia were studied. Each side ...

The enzyme UGT2B7 is one of the most active UDP-glucuronosyltransferases (UGTs) involved in drug metabolism and in maintaining homeostasis of endogenous compounds. We recently reported the existence of 22 UGT2B7 mRNAs, two with a classic 59 region but alternative 39 ends namely UGT2B7_v5 (containing a novel terminal exon 6b) and _v7 (exon 5 excluded) that encode enzymatically inactive isoforms ...

Tourniquet application is a widely accepted adjuvant technique in extremity surgery. The purpose of this prospective, randomized trial was to evaluate the effect of cuff width on skeletal muscle ischemia-reperfusion injury. A 2- or 4-cm wide curved tourniquet cuff was applied around the midthigh of 36 New Zealand White rabbits and inflated to a pressure of 200 or 400 mm Hg for 2 hours: group A=...

We have investigated the partitioning of solutes at crystal defects in intergranular Cr-rich M2B borides after creep 850°C/185MPa and annealing 850°C for approximately 3000 h a polycrystalline nickel-based superalloy. Borides were found to coarsen both cases, with being thickest (800–1100 nm), compared annealed absence an external applied load (400–600 nm). Transmission electron microscopy reve...

this study was carried out to determine the optimal irrigation intervals in sugar beet seed production fields and to evaluate the effects of irrigation at different growth stages of sugar beet seed bearing plants (cv. shirin) on seed qualitative and quantitative characteristics. the treatments were four irrigation intervals including a control (i1) (irrigation at three stages; planting, bolting...

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