In this paper, we study the performance of various IDA*-style searches and investigate methods to improve their performance by predicting in each stage the threshold to be used for pruning. Without loss of generality, we consider minimization problems in this paper. We rst present three models to approximate the distribution of the number of search nodes by lower bounds: exponential, geometric ...

BACKGROUND Iron Deficiency Anemia (IDA) has been controversially linked to IL-4 production in previous studies. A predominant Th1 response leads to resistance against recurrent vulvovaginal candidiasis (RVVC), whereas a Th2 response exacerbates the disease. OBJECTIVE To investigate the possible effect of iron deficiency on the host's susceptibility to RVVC as a result of the Th1/Th2 cytokine ...

In this paper, we study the performance of various IDA*-style searches and investigate methods to improve their performance by predicting in each stage the threshold to use for pruning. We rst present three models to approximate the distribution of number of search nodes by lower bounds: exponential, geometric, and linear, and illustrate these distributions based on some well-known combinatoria...

Background: Iron Deficiency Anemia (IDA) has been controversially linked to IL-4 production in previous studies. A predominant Th1 response leads to resistance against recurrent vulvovaginal candidiasis (RVVC), whereas a Th2 response exacerbates the disease. Objective: To investigate the possible effect of iron deficiency on the host’s susceptibility to RVVC as a result of the Th1/Th2 cytokine ...

In Arabidopsis thaliana, the final step of floral organ abscission is regulated by INFLORESCENCE DEFICIENT IN ABSCISSION (IDA): ida mutants fail to abscise floral organs, and plants overexpressing IDA display earlier abscission. We show that five IDA-LIKE (IDL) genes are expressed in different tissues, but plants overexpressing these genes have phenotypes similar to IDA-overexpressing plants, s...

Motivation: We address the following question: Does inhibition of the expression of a gene X in a cellular assay affect the expression of another gene Y? Rather than inhibiting gene X experimentally, we aim at answering this question computationally using as the only input observational gene expression data. Recently, a new statistical algorithm called Intervention calculus when the Directed ac...

BACKGROUND In Korea, the prevalence of anemia and iron deficiency anemia (IDA) among older infants and young children remains high. To detect IDA early and to reduce its adverse impact, we assessed the characteristics of infants and young children who had IDA or were at risk of developing IDA, or who exhibited characteristics associated with severe anemia. METHODS Among the 1,782 IDA-affected...

In this paper we introduce and study a new class of hybrid automata, Independent Dynamics Hybrid Automata (IDA). IDA are an extension of decidable O-minimal automata in which also identity resets are allowed. We define the conditions under which reachability is decidable over IDA. These conditions involve the satisfiability of first-order formulæ that limit the interval of time we need to consi...

PURPOSE Randomized comparisons of idarubicin (IDA) with daunorubicin (DNR) show that in adults with acute myeloid leukemia (AML), IDA achieves higher remission rates and longer remission durations. In Children's Cancer Group Pilot Study CCG-2941, we assessed toxicity and feasibility of substituting 4 mg of DNR with 1 mg of IDA in intensive-timing daunorubicin-based induction therapy (DNR/DNR) u...

Models of landscape evolution or hydrological processes typically depend on the accurate determination of upslope drainage area from digital elevation data, but such calculations can be very computationally demanding when applied to high-resolution topographic data. To overcome this limitation, we propose calculating drainage area in an implicit, iterative manner using linear solvers. The basis...