Self-harm behaviors are a major public health concern across the lifespan, particularly among individuals with psychiatric disorders. Little research, however, has examined these behaviors among individuals with a diagnosis characterized by recurrent acts of impulsive aggression, Intermittent Explosive Disorder (IED). Furthermore, extant research has not examined variables that might mediate th...

Humans with lesions to the orbital/medial prefrontal cortex and interconnected areas display impulsive aggressive behavior. To examine further the relationship between impulsive aggression and orbital/medial prefrontal dysfunction, we measured the behavioral performance of psychiatric patients with a disorder characterized by impulsive aggression, Intermittent Explosive Disorder (IED). Presentl...

We investigated the correlation of interictal epileptiform discharges (IED) in routine EEG 6 and 24 months after epilepsy surgery with regard to long-term seizure outcome. In 148 patients (74% temporal lobe epilepsy (TLE), 26% extratemporal epilepsy) EEG results (IED present or absent) were correlated with the postoperative outcome using the Engel classification 6 and 24 months after resection ...

Conceptualizations of Intermittent Explosive Disorder (IED) have suffered from a scarcity of research investigating the subjective experience and phenomenology of the aggressive outbursts among those with IED relative to those who partake in more normative forms of aggression. Furthermore, though some studies have shown that individuals with IED are more impaired and have a poorer quality of li...

Com exceção do Brasil, os países da América Latina expandiram consideravelmente suas redes de tratados bilaterais investimento (TBIs), durante anos 1990, na busca ampliar o ingresso estrangeiro direto (IED). Apesar a teoria sobre tema prever uma relação positiva entre IED e celebração desses acordos, literatura empírica não é conclusiva respeito quais impactos TBIs exercem IED, tornando incerto...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: e pilepsy is a common, chronic neurological disorder that affects more than 40 million people worldwide. epilepsy is characterized by interictal and ictal functional disturbances. the presence of interictal epileptiform discharges (ieds) can help to confirm a clinical diagnosis of epilepsy, and their location a...

BACKGROUND Evidence suggests that impulsive aggression and explosive anger are common among individuals with anxiety disorders; yet, the influence of intermittent explosive disorder (IED) on the onset, course, consequences, and patterns of comorbidity among those with anxiety disorders is unknown. METHODS Data were drawn from the National Comorbidity Survey Replication (N = 9,282) and Adolesc...

The U.S. military, despite spending over $13 billion, appears powerless to stop the Iraqi insurgency’s improvised explosive devices (IEDs), which cause most of the military’s casualties and prevent victory by showing lawlessness and insecurity. However, this view ignores substitution effects we consider here. Using rational choice and expectations models, we find a backward-bending supply curve...

INTRODUCTION EEG-fMRI detects BOLD changes associated with epileptic interictal discharges (IED) and can identify epileptogenic networks in epilepsy patients. Besides positive BOLD changes, negative BOLD changes have sometimes been observed in the default-mode network, particularly using group analysis. A new fast fMRI sequence called MREG (Magnetic Resonance Encephalography) shows increased se...

AIMS Scalp-EEG interictal epileptiform discharges (IEDs) may be less predictive of the outcome of frontal lobe epilepsy surgery than of temporal lobe epilepsy surgery. We identified factors associated with the location of scalp-EEG IEDs in intractable frontal lobe epilepsy. METHODS Ten factors were assessed in a retrospective review of 53 patients with either concordant (frontal lobe seizure ...