Passive hemagglutination assays (PHA) may be used to detect IgA antibodies to confirm clinical diagnoses of suspected IgA anaphylactic transfusion reactions. Passive hemagglutination inhibition assays (PHIA) may be used to identify IgA-deficient blood donors whose plasma-containing components are transfused to prevent anaphylactic transfusion reactions in prospective recipients at risk because ...

Background: The study of antiphospholipid antibodies (aPL), not included in the Sydney diagnostic criteria, syndrome (APS) and systemic lupus erythematosus (SLE) is poorly understood. Objectives: To determine frequency detection IgA-aCL IgA-aβ2GP1 IgG to β2GP1 domain 1 (IgG-aβ2GP1-D1) patients with APS without SLE. Methods: ELISA chemiluminescence assays (CMA) were used test 63 sera patients: 2...

Immunoglobulin A (IgA) is the primary immune response induced in the intestine by rotavirus infection, but vaccination with virus-like particles induces predominantly IgG, not IgA. To definitively assess the role of IgA in protection from rotavirus infection, IgA knockout mice, which are devoid of serum and secretory IgA, were infected and then rechallenged with murine rotavirus at either 6 wee...

Because abnormalities of mucosal immunity have been suggested in human IgA nephropathy, we examined the involvement of mucosal immunity in IgA deposition to the kidney in hyper IgA (HIGA) mice, which was established as a mouse model for human IgA nephropathy with hyperserum IgA. The number of surface IgA+B220- lymphocytes in the intestinal lamina propria (LP) of HIGA mice increased 2.7-fold at ...

background: mild to severe post-transfusion adverse reactions have been reported in a proportion of immunodeficient patients receiving intravenous immunoglobulin (ivig). anti-iga antibody has been proposed to be associated with development of such reactions.   objective: to assess the association between anti-iga levels of different isotypes and adverse reactions induced in immunodeficient pati...

To determine the morphometric landmarks and anatomical variants relevant to arthroscopic approach deep gluteal space. Twenty spaces from cadaveric specimens were dissected. The of sciatic nerve (SN) determined according Beaton Anson classification. A study distances in subgluteal space was carried out define references achieve a safe for piriformis syndrome [GT-SN=Distance greater trochanter (G...

objective: diabetes mellitus as the most common metabolic disease of human has wide range of oral consequences such as oral infections which could make changes in the properties of saliva. the purpose of this study was to compare the amount of salivary iga in diabetic and non-diabetic patients. materials and methods: in this case-control study, the population consisted of 40 persons including 2...