Background: In this study we have prepared the IgA solution from normal human plasma using plasma fractionation and ion exchange chromatography. Materials and Methods: Using fractionation of plasma with cold ethanol (starting with 8% ethanol), fraction III was prepared as a suitable source for IgA preparation. Then it was treated with caprylic acid for separation of impurities. For enrichm...

Background: The airway surfaces are one of the most common ways of entry of infectious agents. Oral cavity associated lymphoid tissues are inductive site of humoral immune responses in inflammatory and infectious disorders of the upper respiratory tract. These lymphoid tissues play important roles in the induction of salivary IgA. The impact of upper respiratory tract diseases on salivary IgA p...

background: the airway surfaces are one of the most common ways of entry of infectious agents. oral cavity associated lymphoid tissues are inductive site of humoral immune responses in inflammatory and infectious disorders of the upper respiratory tract. these lymphoid tissues play important roles in the induction of salivary iga. the impact of upper respiratory tract diseases on salivary iga p...

background: in this study we have prepared the iga solution from normal human plasma using plasma fractionation and ion exchange chromatography. materials and methods: using fractionation of plasma with cold ethanol (starting with 8% ethanol), fraction iii was prepared as a suitable source for iga preparation. then it was treated with caprylic acid for separation of impurities. for enrichment o...

selective deficiency of immunoglobulin a (iga) is the most frequent primary hypogammaglobulinemia. as some iga-deficient patients have iga antibodies in their plasma which may cause anaphylactic reactions, blood centers usually maintain a list of iga-deficient blood donors to prepare compatible blood components. in this study we determined the incidence of selective iga deficiency (sigad) in no...